Senior Experimental Scientist

14 hours ago


Cambridge, Cambridgeshire, United Kingdom SRG Full time
Job Description

This is an integral role which requires impact and a purposeful approach in both in vitro and in vivo experimental science projects across the DMPK drug discovery process.

We are seeking a highly skilled Senior Experimental Scientist to lead our Medicinal Chemistry and DMPK group. As a key member of our team, you will be responsible for suggesting, crafting, and carrying out innovative experiments within an expert team of DMPK and PKPD Scientists.

The core role requirements include:

  • Suggesting next steps in the experimental process and evaluation of novel techniques.
  • Contribution to the leadership of the Medicinal Chemistry and DMPK group and the Therapeutic innovation strategy.
  • Management of outsourcing activity and operational resources to ensure effective delivery of projects.
  • Overseeing internal expertise, apportioning capacity and resources which inform governance and decision-making around portfolio support and technology development.
  • Ensuring consistent high-quality data integrity within the DMPK group, presenting compelling data interpretation to guide research strategy and direction.
Requirements

To succeed in this role, you will need:

  • A PhD or equivalent in Pharmaceutics, Pharmacology, Drug Metabolism or Pharmacokinetics (or closely related), covering a deep and broad element of modelling and simulation (quantitative pharmacology, systems biology, pharmacometrics, applied maths for example).
  • Proven expertise in the DMPK space for drug discovery.
  • Demonstrable track record of delivering PK, PKPD and TKPD expertise to projects including mechanistic PKPD modelling for therapeutic dose prediction.
  • Highly skilled in use of MATLAB, SimCYP, WinNonLin/Phoenix NLME.
  • A wide and varied personal network; accustomed to presenting and publishing your work in recognised leading journals.
  • Strong influencing skills, able to lead with credibility and compelling communication skills, both in person and written form.
  • Accustomed to working in a diverse team setting across multiple sites with both internal and external stakeholders to consider.
About Us

We offer a competitive salary up to £76k per annum, commensurate with experience. This includes a range of benefits and a chance to work on challenging and rewarding projects in the field of DMPK drug discovery.


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