Postdoctoral Research Scientist

2 months ago


York, York City, United Kingdom University of York Full time
Job Title: Postdoctoral Research Associate

We are seeking a highly motivated and experienced Postdoctoral Research Associate to join our team at the University of York. The successful candidate will have a strong background in molecular biology, cell biology, or microbiology and will be responsible for conducting high-quality research in the field of autophagy, lysosome exocytosis, and biomolecular condensates.

Key Responsibilities:
  • Validate and optimize high-throughput live imaging systems combined with gene silencing screens of protein kinases.
  • Conduct autophagy-related proximity labelling, phospho-proteomic, and mass spectrometry analysis.
  • Develop and implement assays for protein interaction and enzyme activity using biophysical and biochemical approaches.
  • Generate mutated cell lines by CRISPR/Cas9 mediated precision editing and perform phenotypic validation in vitro and in murine models.
  • Purify and analyze biomolecular condensates by mass spectrometry and sequencing.
Requirements:
  • PhD in Molecular Biology, Cell Biology, or Microbiology.
  • Strong knowledge in molecular biology, parasitology, and modern techniques.
  • Experience in cell culture, handling of class 2 pathogens, murine infection, and gene editing is desirable.
  • Excellent track record of research publications and highly developed communication skills.
  • Attention to detail, collaborative ethos, and interest in co-supervising students.
  • Positive attitude to colleagues and students, and a willingness to work proactively.
  • Commitment to personal development and understanding of equality and diversity issues.
What We Offer:

The University of York is committed to being a diverse and inclusive place of work. We particularly encourage applications from people who identify as Black, Asian, or from a Minority Ethnic background, who are underrepresented at the University. We offer family-friendly, flexible working arrangements, with forums and inclusive facilities to support our staff.



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