Protein Research Scientist

4 weeks ago

Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full time
Job Title: Research Scientist, Protein

We are seeking a highly skilled Research Scientist to join our Protein & Cellular Sciences Team at Bicycle Therapeutics. As a key member of our team, you will be responsible for designing and producing high-quality cellular and recombinant protein material to support our Bicycle Discovery platform.

Key Responsibilities:
  • Protein & Cellular Material Supply: Develop and implement strategies to supply high-quality protein & cellular material to support the Bicycle Discovery platform.
  • Research and Development: Conduct research into target biology and source necessary reagents to evaluate new targets.
  • Cell Culture and Maintenance: Maintain adherent and suspension cells to supply the wider team and ensure the day-to-day running of the tissue culture facility.
  • Data Analysis and Presentation: Help present data and conclusions to project teams in oral or written form, including possible next steps to drive projects forward.
Qualifications:
  • Educational Background: Educated in life sciences relevant to the role or equivalent qualification.
  • Experience: Experience of working in a biotech or industrial environment or equivalent.
  • Molecular Biology: Experience in design & propagation of DNA expression plasmids (restriction enzymes).
  • Mammalian Cell Culture: Experience in mammalian cell culture, including aseptic technique, subculture of suspension and/or adherent cell lines, transfection, cryopreservation, etc.
  • Flow Cytometry: Theoretical knowledge of flow cytometry.
  • Interpersonal Skills: Strong interpersonal skills, confident and experienced in presenting data.
Desirable Qualifications:
  • Flow Cytometry & Cell Sorting: Practical experience of flow cytometry & cell sorting.
  • Molecular Biology: Molecular biology experience in DNA assembly and cloning (Gibson, HiFi, Golden Gate).
  • Protein Expression Analysis: Experience in protein expression analysis (qPCR, SDS-PAGE & Western Blotting) and subsequent purification (AKTA).
What We Offer:
  • State-of-the-art Campus Environment: Work in a state-of-the-art campus environment with on-campus restaurant and Montessori nursery.
  • Flexible Working Environment: Enjoy a flexible working environment with competitive rewards.
  • Employee Recognition Schemes: Participate in employee recognition schemes and annual company bonus.
  • Benefits: Enjoy a range of benefits, including private medical insurance, life assurance cover, and employee assistance program.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.

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