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Laboratory Research Associate
2 months ago
The London School of Hygiene & Tropical Medicine (LSHTM) stands at the forefront of global public health education and research. Our commitment is to enhance health and health equity both in the UK and internationally, fostering partnerships to excel in public health initiatives.
Role Summary:We are looking to recruit two dedicated Research Assistants to join our tuberculosis translational biology research team. This initiative aims to innovate new antibiotic treatments for tuberculosis, supported by funding from Janssen Pharmaceutica. The project encompasses the creation of advanced molecular biology tools to explore pathogen biology, alongside standard bacteriology methodologies utilized in laboratory settings.
Key Responsibilities:- Operate within a containment level 3 laboratory environment.
- Implement routine genetic methodologies, including CRISPR-based knockdown and target overexpression.
- Conduct regular evaluations of new drug candidates through assays such as MICs, MBCs, and kill kinetics.
- Utilize and develop fundamental bacteriology and microbiology techniques to assess new drug targets for tuberculosis through chemical genomics and proteomics.
- Collaborate within cross-functional teams, including industry partners, in a dynamic international research setting.
We seek individuals with a relevant undergraduate degree in biochemistry, microbiology, life sciences, or equivalent qualifications. Ideal candidates will possess experience in genetic manipulation, susceptibility testing, and bactericidal assays, particularly related to M. tuberculosis. Proficiency in molecular biology techniques, such as molecular cloning and RNA/DNA preparation, is essential. Experience in a Biosafety Level 3 laboratory with knowledge of MICs, MBCs, RNA/DNA isolation, and bacterial transfection is advantageous.
Successful candidates will demonstrate strong organizational abilities, effective time management skills, and the capacity to work both independently and collaboratively within a research team. Excellent interpersonal skills, including strong oral and written communication, are also crucial.
Employment Details:This is a full-time position, comprising 35 hours per week, with a fixed-term contract. The role is funded by Janssen Pharmaceutica and offers a competitive salary on the Academic Pathway salary scale, Grade 5, within the range of £38,282 - £43,947 per annum (inclusive of London Weighting). Additional benefits include annual leave entitlement and membership in the Pension Scheme.
