Biotransformation Development Lead

3 weeks ago


Berkshire, United Kingdom Hyper Recruitment Solutions LTD Full time
Biotransformation Development Lead Opportunity

We are seeking a highly skilled Biotransformation Development Lead to join our team at Hyper Recruitment Solutions Ltd. As a key member of our science and technology recruitment team, you will be responsible for contributing to the development and drug discovery projects in immunology and neuroscience therapeutic areas.

Key Responsibilities:
  • Plan, perform, and interpret metabolite profiling studies up to and including human ADME studies for regulatory submissions, including MIST evaluation.
  • Plan and coordinate outsourced metabolite profiling studies in partnership with Contract Research Organisations.
  • Provide guidance in line with regulatory requirements and apply this to biotransformation strategies.
  • Generate, report, and communicate metabolic profiles in different biological matrices from in vitro and/or in vivo studies, including active and reactive metabolites by interpretation of mass spectral data.
Requirements:
  • Relevant degree in Biotransformation, DMPK, or related areas with analytical chemistry experience.
  • Extensive industry experience in biotransformation and metabolism, particularly in supporting preclinical and clinical leads.
  • Working knowledge and practical experience in metabolite identification experience in LC/MS, bioanalytical chemistry, and enzymology, as well as strong knowledge of international regulatory principles and guidelines regarding human metabolites with particular emphasis on MIST.

Hyper Recruitment Solutions Ltd is an Equal Opportunities employer. We welcome applications from candidates who meet the role requirements. If you are a motivated and experienced professional looking for a new challenge, please submit your application.



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