Senior Scientific Manager
1 month ago
We are seeking an experienced Group Leader/Senior Group Leader to join our Structural Biology, Biophysics and Protein Science management team at Charles River Laboratories.
About the RoleThis is a key leadership position that will provide strong scientific, operational and strategic leadership to multiple teams at our Harlow and Chesterford Research Park sites. The successful candidate will be responsible for project feasibility scoping, delivery and management review of high quality scientific proposals for challenging targets across the department's main discipline areas.
Key Responsibilities- Scientifically:
- Responsible for project feasibility scoping with production, delivery and management review of high quality scientific proposals for challenging targets across the department's main discipline areas.
- Able to provide an expert level of support and troubleshooting to team members in one or more disciplines of:
- Structural Biology - Crystallisation, Liquid handlers, X-ray Crystallography, Cryo-EM
- Protein Science - Construct Design, Protein Expression across Prokaryotic and Eukaryotic hosts, Protein Purification on AKTA platform (extensive range of Chromatography techniques), Protein Characterisation (HPLC-SEC, DLS, DSF)
- Biophysics - SPR (Biacore and Bruker), Protein NMR, ITC, Fragment Screening
- People Leadership:
- Line management of up to 8 direct reports (scientific staff) in accordance with company directions and policies.
- Responsible for performance reviews, succession planning, development and training of team members.
- To mentor and coach team members in achieving their potential and advancing their careers.
- To ensure that all relevant reports operate in a safe manner at all times and ensure compliance with CRL site-based safety and compliance guidelines.
- To guide members of the team in technical aspects of your core discipline, aiding in assembly and presentation of complex datasets to our clients.
- Adopt a strategic role to future-proof the department from both technological and resourcing perspectives, working with the wider departmental management team.
- Contribute to the management and performance of the Protein Science, Biophysics and Structural Biology team by taking on selected responsibilities.
- Lead scientific projects and project teams aimed at maintaining client satisfaction as well as delivery on project objectives and financials.
- Apply a dynamic and flexible approach towards achieving client-based objectives and meeting challenging deadlines as required.
- Communicate confidently and concisely with clients via video conference, presentation, and written reports.
- In addition to leading their own projects, the successful candidate will be comfortable communicating across Charles River Laboratories global sites to drive efficiencies and enhance best practice.
- A minimum BSc in a related discipline, a PhD (or equivalent experience) in a field of relevance to structural biology and protein sciences is highly advantageous.
- Crystallisation expertise in an industrial or core facility group within a structural biology drug discovery environment is very desirable.
- Project leadership experience.
- Proven track record of impacting upon projects.
- Evidence of drug discovery project leadership.
- Experience as discipline lead in an integrated drug discovery project.
- Excellent interpersonal, communication and presentation skills.
- A dynamic and flexible approach towards achieving client-based objectives and demonstrable ability to deliver on multiple simultaneous projects with challenging deadlines.
- Specific experience of performance management.
- Experience within a CRO setting is desirable.
- A very comprehensive benefits package from day one, including a generous pension contribution, private medical, bonus, private dental, critical illness cover and more.
- Access to great discounts via our CREDS discount scheme.
- Parental leave.
- Group Life Assurance and Group Income Protection.
- Remote GP access 24/7.
- Well-being support and initiatives.
- Global opportunities and strong career progression.
- The chance to work on several varied projects and liaise globally and nationally with other business areas.
- To be able make a difference to health and wellbeing of people.
- To continue your own career growth.
- Flexible and hybrid working.
- Cycle to work scheme.
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