Associate Director, Non-Clinical Pharmacokinetics Specialist
4 weeks ago
We are seeking a highly skilled and experienced Associate Director to lead our Non-Clinical Pharmacokinetics team. As a key member of our organization, you will be responsible for driving strategy and supporting projects by exploring PK/PD relationships in pre-clinical models.
About the RoleYou will be an integral part of the team, working closely with cross-functional groups to develop and execute effective nonclinical PKPD strategies from early discovery through to clinic. Your expertise in pharmacology and PKPD methods will be essential in translating in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients.
Key Responsibilities- Develop and drive the nonclinical PKPD strategy for projects, ensuring effective communication and implementation.
- Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients.
- Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build a thorough knowledge of drug pharmacology and PKPD.
- Build PKPD models to allow hypothesis testing and inform decision-making.
- Provide scientific and technical input, expertise, and leadership to Non-clinical PKPD group, project teams, and the department.
- Work in collaborations with external partners, academic institutions, CROs, and consultants as required.
- Maintain an awareness of new/emerging techniques and tools relevant to the field.
- Represent the interests of QCP internally and externally in matters relevant to mechanistic PKPD and contribute to enhancing the scientific reputation of Non-Clinical PKPD.
- As required, contribute to Due Diligence of external project, product, and technology opportunities.
- Provide required support and input into regulatory study protocols, reports, and summaries, and regulatory submission documents.
- PhD in a relevant discipline (pharmacology, bio/engineering, pharmacokinetics/pharmacodynamics, etc.).
- Good understanding of pharmacology and the pharmacology processes related to disease and drug mechanisms.
- Expertise and proven application of PKPD methods and concepts in support of drug discovery and development. Systems modelling experience would be advantageous.
- Demonstrated experience in developing and executing effective nonclinical PKPD strategies from early discovery through to clinic.
- Innovative, self-motivated, team-oriented scientist with good written and verbal communication skills, able to handle several projects at any given time, to work successfully in teams and to communicate clearly to a variety of audiences.
- Demonstrated leadership skills in a matrix environment, capable of working effectively in teams and influencing relevant stakeholders.
- Experience working within a matrix environment with a wide range of internal stakeholders including Non-Clinical Safety, Bioanalysis, Clinical Pharmacology, and Translational Medicine.
- Record of publications and other external scientific contributions relevant to PKPD.
- Experience in using modelling and simulation packages such as Phoenix, Berkeley Madonna, Monolix, R.
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Slough, Slough, United Kingdom Lifelancer Full timeJob Title: Associate Director, Non-Clinical PharmacokineticsWe are seeking a highly skilled and experienced Associate Director to lead our Non-Clinical Pharmacokinetics (PKPD) team. As a key member of our organization, you will be responsible for driving the development and implementation of PKPD strategies for our projects.About the RoleYou will be an...
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Slough, Slough, United Kingdom Lifelancer Full timeJob Title: Associate Director, Non-Clinical PharmacokineticsWe are seeking a highly skilled and experienced Associate Director to lead our Non-Clinical Pharmacokinetics (PKPD) team. As a key member of our organization, you will be responsible for driving the development and implementation of PKPD strategies for our projects.About the RoleYou will be an...
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