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Director, Protein Degradation and Medicinal Chemistry

2 months ago


Fulbourn, Cambridgeshire, United Kingdom Amphista Therapeutics Ltd Full time
About the Role

We are seeking a highly experienced and skilled Senior Director to lead our Medicinal Chemistry and Pharmacokinetics team at Amphista Therapeutics Ltd. As a key member of our R&D leadership team, you will be responsible for driving the discovery and development of novel protein degrader-based medicines.

Key Responsibilities
  • Lead and contribute to the development of our protein degrader drug discovery and development programs, with a focus on degrader bRo5 compounds.
  • Manage a team of external consultants and potentially lead a team of scientists to deliver project goals and candidate molecules for development.
  • Collaborate with project teams, medicinal chemistry, biology, pharmacology, and development leaders to advance therapeutic programs and deliver results.
  • Develop and implement new strategies and ways of working to advance specific projects and systems, with a focus on data quality and productivity.
  • Monitor, measure, and report on scientific issues, opportunities, and developmental plans and achievements within agreed formats and timescales.
Requirements
  • PhD in a relevant field, such as medicinal chemistry, pharmacology, or a related discipline.
  • Proven track record of leading and contributing to the discovery and development of novel medicines, with a focus on protein degrader-based approaches.
  • Strong leadership and management skills, with experience of managing teams and collaborating with cross-functional teams.
  • Excellent communication and interpersonal skills, with the ability to present plans and results to senior leadership and project teams.
  • Ability to work in a fast-paced environment and prioritize multiple tasks and projects.
What We Offer
  • Competitive salary and benefits package.
  • Discretionary bonus scheme and pension scheme with employer-matched contribution.
  • 25 days holiday plus bank holidays and holiday buy scheme.
  • Opportunity to work with a dynamic and growing company at the forefront of protein degradation-based drug discovery.