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Quantitative Systems Pharmacology Lead

2 months ago

Cambridge, Cambridgeshire, United Kingdom CK Group Full time

{"title": "Associate Director Quantitative Systems Pharmacology Translational Medicine", "company": "CK Group", "responsibilities": ["Lead efforts to embed Quantitative Systems Pharmacology strategies to Nxera programs to aid in drug discovery decisions including target prioritisation, biomarker characterisation and early clinical trial design.", "Develop and assess the functionality, feasibility, efficiency and validity of new QSP models.", "Collaborate extensively with internal and external cross-functional teams to develop and apply QSP models across a portfolio of therapeutic compounds.", "Guide and shape the way in which QSP led approaches are applied to address drug discovery and development questions.", "Embed QSP strategy as part of the project translational plans and demonstrate its utility in supporting clear decision making through to early clinical trials.", "Develop and apply QSP/Systems Biology models.", "Use advanced mathematical modeling and simulation techniques.", "Competently use modeling software(s) such as Matlab/SimBiology and programming / data analytical skills using languages such as Python or R.", "Manage outsourced studies with CROs or academic partners.", "Apply pharmacokinetics and pharmacodynamics principles in Drug Discovery and development."]}