Brc Clinical Research Fellow

5 months ago

Liverpool, United Kingdom The Clatterbridge Cancer Centre NHS Foundation Trust Full time

This post is a full time appointment for an initial period of 12 months to provide medical support to the Urology Trials team including consultants, nursing and administration staff. The successful applicant will analyse data from the PIVOTALboost trial and write up radiotherapy quality assurance projects performed as part of this trial. The post-holder will also conduct AI guided analysis of MRI boost volumes.

**Research**: In addition to the research projects outlined above, the post-holder may be involved with new patient consultation, consent and screening patients for radiotherapy and systemic therapy trial and reviewing patients at follow-up appointments. The appointee will also be able to attend urology outpatient clinics, dependant on the needs of their research project.

**Professional Development**: You will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and you will be expected to be involved in audit, writing papers and reviews. You will also be required to undergo an annual appraisal.

**Clinical Governance**: You will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the Urology Trials team.

**Role Planning**: This is a 10 session out of program specialty registrar (full) level post funded through The Clatterbridge Cancer Centre BRC collaboration for an initial period of 1 year (with potential to extend to 2 years).

The Clatterbridge Cancer Centre is one of three specialist cancer centres in England. With 1,800 specialist staff and three sites, we are one of the largest NHS providers of non-surgical cancer treatment. The Trust has a unique multi-site care model serving the 2.4 million population across Cheshire and Merseyside and is consistently rated by patients as one of the best performing hospitals.

Our vision is to not only maintain this level of commitment to excellence but to work with our academic and healthcare partners across the region to ensure care, treatment and patient outcomes continuously improve in the future. We are very proud of all our expert and loyal staff and we welcome people who share the collective aim of delivering excellence in everything that we do.

Our values represent who we are and what we believe in. They define how we act to deliver the best possible care for our patients and shape The Clatterbridge Cancer Centre as a great place to work.
We are
- Kind
Empowered
Responsible
Inclusiv e

CCC is now part of a Biomedical Research Centre (BRC) in partnership with The Royal Marsden, one of the most prestigious cancer centres in the world. The applicant will collaborate with the Urology team (Lead Dr Alison Tree) as part of the research project.

You will have the opportunity to be involved in recruiting and treating patients in urology trials, auditing, writing papers and reviews and there is the potential to present research work at meetings and conferences.

The position requires an ability to understand and use MRI imaging data and radiotherapy planning systems. The applicant will learn to critically assess and analyse results from prostate radiotherapy trials; liaising across a range of clinical, academic and administrative staff throughout the Trust and the University of Liverpool.

**Aim/Work stream 1**: The project will evaluate how different factors (including deprivation score and research funding) influenced recruitment into PIVOTALboost or PACE A, B and C trials UK wide.

**Aim/Work stream 2**: The two PIVOTALboost RTQA benchmark cases will be evaluated against Simultaneous Truth and Performance Level Estimate (STAPLE) contours; the geometric variability will be compared with dose volume parameters, tumour control probability and normal tissue complication probability from re-planned individual submissions.

**Aim/Work stream 3**: With in collaboration with the radiology team, AI generated boost contours are produced from BIOPROP cohort studies (Clatterbridge phase II cohorts, training set); from two PIVOTALboost trial centres, evaluate the AI generated contours with contours generated by PI and an expert panel (validation set).

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