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Research Associate
3 months ago
Applications are invited for a Research Associate - Genome Editing Unit position to work with investigators at the Discovery Research Platform for Cell-Matrix Biology.
This is a full time appointment starting 1 July 2024, or as soon as possible thereafter, and is for a fixed term until June 2027. Should the appointment prove successful, there is an opportunity for a further 4 years.
The Manchester Cell Matrix Centre (MCMC) brings together diverse research groups with academic, technology and computational expertise to overcome barriers in extracellular matrix research. Extracellular matrix is essential for multicellular life, it surrounds and supports cells and accounts for one third of our body mass. Defining the principles that govern the two-way interaction between cells and matrix is fundamental to understanding vertebrate development, healthy ageing, and identifying why tissue failure is a major factor in most chronic diseases.
Located at The University of Manchester, the Centre incorporates one of eight Discovery Research Platforms recently awarded by the Wellcome Trust. The Discovery Research Platform for Cell-Matrix Biology will address practical, technological, and methodological barriers to understanding how changes in the extracellular matrix leads to tissue failure.
This role will support the development of novel technologies and approaches to investigate and better understand matrix biology, particularly in vivo. The successful applicant will liaise directly with Platform and Centre investigators, to understand their research goals and will devise novel experimental tools and strategies for Matrix biology research. Whilst the person will be a member of the GEU team based in the Michael Smith building, importantly we expect a proportion of the time will be spent working with Platform laboratories on defined projects. The appointee will be part of a larger consortium of technology focussed scientists within the Platform working on developing novel toolkits and approaches for cutting edge extracellular matrix research.
A key feature of the role will be to exploit our existing expertise in genetic manipulation technologies and to integrate and/or develop other cutting-edge GM techniques (e.g. base editing, prime editing, CRISPRi and CRISPRa, saturation mutagenesis, PROTACs, LYTACs etc) and genetically encoded reporter systems where required on relevant projects.
What you will get in return:
- Fantastic market leading Pension scheme
- Excellent employee health and wellbeing services including an Employee Assistance Programme
- Exceptional starting annual leave entitlement, plus bank holidays
- Additional paid closure over the Christmas period
- Local and national discounts at a range of major retailers
- Our University is positive about flexible working you can find out more _here_
Hybrid working arrangements may be considered.
Any CV’s submitted by a recruitment agency will be considered a gift.
**Enquiries about the vacancy, shortlisting and interviews**:
Name: Antony Adamson
**General enquiries**:
**Technical support**:
**Please see the link below for the Further Particulars document which contains the person specification criteria.
