Clinical Research Associate

3 weeks ago

Newcastle upon Tyne, United Kingdom Newcastle University Full time

**Salary**: £31,623 to £40,492 per annum

Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

**Closing Date**: 04 July 2023

The Role

An exciting opportunity has arisen for an ambitious clinician to join the team at the John Walton Muscular dystrophy research centre, which has a long tradition of excellence in research, diagnosis, and management of neuromuscular diseases. The post will be based at the Centre for Life at Newcastle University.

The Neuromuscular field is developing rapidly with an increasing pipeline of clinical trials, including gene therapies, in paediatric and adult patient cohorts. In this context, you will participate in neuromuscular clinics across the northern region and gain exposure to state of the art diagnostic capabilities for genetic diseases. You will play a key role in recruitment to and conduct of clinical trials and natural history studies in patients with genetic muscle diseases, with a particular focus on Facioscapulohumeral muscular dystrophy (FSHD).

You will have the opportunity to learn about trial design, outcome measures, muscle imaging and other major aspects of conducting clinical research in rare diseases, as well as to develop knowledge and competence to conduct GCP compliant clinical research. You may also choose to play an active role in exciting translational research projects studying the pathomechanisms leading to muscle degeneration in FSHD and other neuromuscular diseases.

You must have a medical degree and GMC licence to practise. You may be looking to build on current experience in clinical trials, neurology, paediatric neurology, genetics, and research.

The post is offered on a fixed term basis for a period of 2 years.

Key Accountabilities

**Support and conduct clinical trials at JWMDRC**: patient identification and selection, consenting, recruitment, interaction with patients and their families, conducting study visits and study procedures, reporting of adverse events etc) under the supervision of senior members of the clinical research team
Participate in specialised clinical and diagnostic activities including the national referral clinics for rare inherited forms of muscular dystrophies and adult and paediatric clinics for local patients with neuromuscular diseases
Continuously review the literature and technology relevant to JWMDRC work, ensuring a good understanding of other on-going work in the field
Be involved in JWMDRC led clinical research grants, allowing for insight into networking activities and international collaborations
Publish and present high level scientific information including writing and presenting reports relevant to the work being carried out as part of translational research
Support the submission of research proposals to funders where appropriate
Regular liaison with the principal investigators and senior members of the research teams to discuss the ongoing research and next possible steps
Support the clinical initiatives of the Neuromuscular Team, including internal and audits and meetings
Participate to the analysis of muscle magnetic resonance imaging studies in FSHD and other diseases

The Person (Essential)

Knowledge, Skills and Experience
Understanding of clinical trial methodology and GCP Principles
Experience in neuromuscular medicine, neurology, genetics or paediatric neurology (Desirable)
Presentation of work at scientific meetings (Desirable)
Previous research publications (Desirable)

Attributes and Behaviour
Enthusiastic and hard working
Excellent oral communication and writing skills
Team-working skills
Excellent information technology and computing skills
High level of personal organisation
Willingness to undertake work outside of normal working hours
Willingness to travel internationally

**Qualifications**:
MB BS (Medical Doctor, MD) or equivalent from a recognised medical school
Fully registered with the GMC with licence to practice
Good Clinical Practice Training (Desirable)

Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

At Newcastle University we hold a silver Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC.

In addition, we are a member of the Euraxess initiative supporting researchers in Europe.

**Requisition ID**: 25623

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