Research Associate Scientist Microvascular

2 months ago

Manchester, United Kingdom The University of Manchester Full time

An exciting opportunity exists to carry out 12 months of post-doctoral research investigating the impact of septic shock on microvascular function. This position is co-ordinated across the laboratories of Dr Chris Stanley at the Heart Research Institute (HRI), University of Sydney, Australia and Dr’s Adam Greenstein and Harry Pritchard’s small artery group at the University of Manchester, UK. The post, which will be based within the Division of Cardiovascular Sciences at the University of Manchester, is funded from a grant from the UK branch of the HRI and as a condition of funding is open to UK citizens only.

Position details:
The research follows on from the recent work of Dr Stanley’s Nature 2019. 566; p548 and Nat Commun 2021. 12; p6626 and will use cutting edge vascular physiology techniques as used in Dr’s Greenstein and Pritchard’s lab’s (Circulation Research 2021. 128:p1279, PNAS 2020. 116;p21874 and Hypertension 2020. 75; p539). The appointed person will work with microvascular arteries taken from models of septic shock to understand how disease pathology changes membrane potential and calcium signalling. Such changes are hypothesised to drive disease-associated sustained vasodilation, and fatal hypotension. This research will utilise myography, electrophysiology, calcium imaging, and a range of microscopy techniques. As well as leading a project, the successful post-doctoral researcher will also be given fantastic opportunities to collaborate on other projects within the lab and/or within the host institute.

What can you expect in return

The University will actively foster a culture of inclusion and diversity and will seek to achieve true equality of opportunity for all members of its community.

What you will get in return:

- Fantastic market leading Pension scheme
- Excellent employee health and wellbeing services including an Employee Assistance Programme
- Exceptional starting annual leave entitlement, plus bank holidays
- Additional paid closure over the Christmas period
- Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working you can find out more here

Hybrid working arrangements may be considered.

Any CV’s submitted by a recruitment agency will be considered a gift.

Enquiries about the vacancy, shortlisting and interviews:
General enquiries:
Technical support:
Please see the link below for the Further Particulars document which contains the person specification criteria.

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