Research Assistant Neuronal Cell Biologist:

2 weeks ago


Oxford, United Kingdom University of Oxford Full time

**Full-time, Fixed-term until 31 December 2024**

Applications are invited for a Research Assistant neuronal cell biologist to work on a project developing disease-modifying therapies in patient stem cell-derived neuronal models of Parkinson’s. The project, in collaboration with EndLyz, a new company within the Dementia Discovery Fund (DDF) portfolio, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop novel therapies for Parkinson’s by better understanding the cellular and molecular mechanisms through working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson’s patients.

Duties will include undertaking laboratory experiments; interpretation of data; imaging analysis; generation and study of iPSC-derived neurons and cell lines; preparation of data for publication; study the mechanisms of action of modulators of the endolysosomal pathway in cellular models of Parkinson’s; contribute to wider project planning and determine the most appropriate methodologies to test hypotheses. You will have excellent practical experience of working with induced pluripotent stem cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available for 12 months to start on January 1st 2024. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford.

**midday on 28 November 2023.**

Interviews are likely to be held on the
**week beginning 4th December 2023.**

We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. - DPAG Statement of Inclusion


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