Lecturer/senior Lecturer

2 weeks ago


Newcastle upon Tyne, United Kingdom Newcastle University Full time

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

We understand how important the full employment package is to our colleagues at Newcastle University and we are committed to providing a great range of benefits and discounts for all. You can learn more about what is available here on our Benefits Website page.

**Starting Salary**:
**Lecturer Grade F**: £32,348 to £41,155 per annum

**Lecturer Grade G**: £43,414 to £51,805 per annum

**Senior Lecturer**: £53,353 to £61,823 per annum

**Closing Date**: 13 January 2023

The Role

We are seeking an experienced and enthusiastic researcher for this new role of Senior Lecturer / Lecturer in Cancer Drug Discovery Bioscience which is created in the Newcastle University Drug Discovery Unit, an academic partner of Cancer Research Horizons Therapeutic Innovation. This role will be part of an integrated team of cancer biologists, pharmacologists, structural biologists and medicinal chemists, who develop novel, differentiated, small molecule therapies for cancer patients. The group has a substantial portfolio and has contributed to the discovery of two registered cancer medicines and two other oncology drugs currently in clinical trials.

You will develop and expand the key research area of drug discovery bioscience as applied to stratified cancer medicines. You will hold a relevant PhD and have undertaken significant previous training in contemporary drug discovery bioscience, gained in academia, biotech and/or a large pharmaceutical company, with experience of working across multiple therapeutic projects. You will also have experience of the different phases of drug discovery, in particular the selection and validation of new drug targets for oncology, including an appreciation of the translational context and patient stratification. You will be technically proficient in the use and development of current molecular and cellular technologies relevant to target validation and the demonstration of drug action in cells.

This role is positioned in the Translational and Clinical Research Institute, whose mission is to transform understanding of disease mechanisms from the laboratory into real-world benefits for patients. It is also aligned to the Newcastle University Centre for Cancer.

Newcastle University is a world-class research-intensive university that aims to provide an outstanding educational experience to its students. In addition to delivering an active programme of research, you will also contribute to the planning and delivery of undergraduate and postgraduate teaching and supervision.

The University has developed a document, which summaries the range of activities that academic colleagues may be expected to perform.

Interviews are likely to take place early February 2023.

Key Accountabilities
To identify and/or evaluate new therapeutic target opportunities and lead related research in cancer drug discovery bioscience, working closely with bioscientists, structural scientists and medicinal chemists in-house and externally (with collaborators)
To champion new strategies and experimental technologies relevant to cancer drug discovery
To work independently and to take a lead in developing and submitting/ publishing in internationally-recognised journals, to bid for research grants from prestigious funders, and participate in dissemination activities
To create and maintain strong collaborative links with other researchers based in the Institute, Faculty and University, and external partners working in the relevant field of research, and to develop collaborative links with international colleagues working in this area
Promote a research culture that encourages and celebrates a rich diversity in its workforce and that upholds the highest standards for its research integrity, data reproducibility and collaborative spirit
To lead and contribute to undergraduate and postgraduate teaching and assessments; supervise undergraduate and Masters dissertations and postgraduate research students in research projects in cancer research/pharmacology and related areas
To carry out management and administrative duties as deemed necessary, including participation in relevant School and Faculty committees and activities as required by your line manager and the Institute Dean
To act as a personal tutor to a group of students, concerned with students’ academic achievements, and pastoral care

LECTURER LEVEL APPOINTMENT

The Person

Knowledge, Skills and Experience
Knowledge
Evidence of substantial knowledge of contemporary cancer biology, pharmacology, and therapeutics for cancer treatment
Evidence of experience of small molecule drug discovery methods
Knowledge and experience of a range of target validation methods including CRISPR /



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