Research Associate in Microbiology

2 weeks ago

Newcastle upon Tyne, United Kingdom Newcastle University Full time

**Salary**: £33,966 to £44,263 per annum

Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

**Closing Date**: 30 April 2024

The Role

We are seeking a highly motivated Research Associate to join our research team. Initially, there is a project to study a potential metabolic link between DNA replication and envelope biogenesis in Gram-negative bacteria in place. However, we strongly encourage our Research Associate to bring or develop their own ideas to transition to scientific independence after this post.

In order to grow, bacteria enlarge their cell envelope, replicate their DNA and then segregate chromosomes between two daughter cells. These processes are commonly studied in isolation with determinants that coordinate them currently being unidentified. By using an unbiased genetic approach, we have uncovered an important genetic link between the processes of outer membrane (OM) protein biogenesis, lipopolysaccharide (LPS) biosynthesis and DNA replication in Escherichia coli.
The main objective of your post is to study cross-talk between OM biogenesis, LPS synthesis and DNA replication control. The idea is to use a mix of structural biology, biochemistry and high-throughput genetic approaches to determine how initiation of DNA replication is coordinated with cell envelope synthesis for the first time.

This post is fixed term, initially for 2 years with the possibility to extend to up to 3 years.

Please note that if you are successful to this role, you will require medical clearance and a standard DBS check before you can commence in the role.

**For informal enquiries contact**: Manuel Banzhaf.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Key Accountabilities
Although working under the general guidance of an academic or Principal Investigator, the postholder will contribute ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial 'added value'
Develop and carry out the specified project using appropriate techniques and equipment as outlined in the personal requirements
Determine appropriate methodologies for research, with advice and support where required
Begin to write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
Assess research findings for the need/scope for further investigations
Contribute to the writing up of their research for publication and dissemination, either through seminar and conference presentations or through publications
Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
May be involved in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants
Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute
May contribute to events celebrating the public engagement of science/social sciences/humanities
Develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment

The Person

Knowledge, Skills and Experience
Ability to work well as part of a team and rapidly acquire new skills
Likelihood of advanced skills directly related to the research projects
High level of analytical and problem-solving capability
Ability to communicate complex information with clarity and to encourage the commitment of others
Experience of research with clear transferable skills and some experience or awareness of the research environment
Presentations at conferences and/or high-quality publications
Desirable
Previous experience in Gram-negative envelope biology
Previous experience in protein biochemistry
Previous experience in molecular genetics and/or TraDIS or similar genetic high-throughput methods

Attributes and Behaviour
Highly motivated and actively pursue a career in academic science or R&D
Ambitious with a demonstrable drive to succeed and produce work at the highest level
Ability to work independently and as part of a team
Capacity for original thought
Ability to write publications in collaboration with other team members

**Qualifications**:
A PhD in natural science discipline

Newcastle University is a global University where everyone is treated with dignity and respect. A

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