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London, Greater London, United Kingdom VONQ Full timeJob DescriptionThe increasing demand for high-quality, robust real-world evidence (RWE) from real-world data (RWD) requires GSK to access and partner with the external RWD environment to ensure evidence generation meets the highest standards. The RWD Strategy team is a small team in Biostatistics, R&D tasked with realizing the potential of RWD and RWE. The...
Associate Director, Real-world Analytics
3 months ago
**Site Name**: Home Worker - USA, Home Worker - CAN, Home Worker - GBR, Wavre
**Posted Date**: Jun 18 2024
The Real-World Analytics (RWA) Scientist, uses data and methodological expertise to develop study designs and statistical analysis plans (SAPs) for the analysis of existing complex health data sets, including real-world data (RWD). This work is conducted in collaboration with Scientists in the Epidemiology and Medical Evidence Generation organizations, and other colleagues as part of matrix teams. These teams work to translate evidence needs into a robust program of studies to support appropriate access to and evidence for GSK medicines. Your work will focus primarily on the Respiratory & Immunology Research Unit, including Respiratory, Hepatology, Neurodegeneration, Connective Tissue, Renal, and Immuno-inflammation/Dermatology disease areas.
**SPECIFIC RESPONSIBILITIES**
**Design and Analysis**
- Manage a portfolio of work or individual studies to ensure delivery of quality work products to agreed timelines
- Share RWD and methodological expertise with asset and TA teams, the broader RWA community, and/or bring that expertise to a matrix team to inform study planning, development, and delivery
- Lead the development and delivery of analysis of existing or new complex health data sets. Responsibilities include: author protocol/statistical analysis plan (includes selecting approach to quantitative bias control, statistical power/precision, sample size), write programming code to conduct statistical analysis, critically review approach and results on an ongoing basis considering design assumptions and knowledge of the data, summarize analytic findings (including limitations) in oral or written form
- Author specifications for analytic data sets for all RWA activities (rapid data queries (RDQ), retrospective observational studies, and other studies) to ensure appropriate interpretation and implementation of analytic design, in collaboration with RW Data Management and Programming (RWDMP). Review resulting deliverable(s) for accuracy/completeness
- Ensure documentation is appropriate regarding data manipulation, statistical analysis, reporting
- Author, maintain, finalize, and archive project delivery documentation for in-sourced studies in accordance with SOPs where appropriate
- Perform quality control (QC) of work products from other colleagues
- As needed, provide RWD and methodological expertise to support study teams in out-sourced studies
**Communication of Results**
- Assist with, or be responsible for, oral and written communication of analytic and study results
- Co-author and bring statistical/methodological expertise in scientific publications of the in
- or out-sourced RWD studies/analyses
- Effectively present research results to study team and other collaborators, including results interpretation and drawing appropriate inferences based on study design/statistical methods as well as assessment of study limitations
**Therapy Area Knowledge**
**Leadership and Teamwork**
- Build and maintain effective strategic working relationships with internal and external partners to meet business needs
- Maintain currency with methods for the use of existing complex health datasets for research
- Develop in depth knowledge on the assigned asset and act as an RWA consultant within broader Evidence Generation and Epidemiology teams
- Merge scientific thinking and business knowledge to identify issues, evaluate options, and implement solutions
- Proactively influence team members regarding appropriate research/statistical design and analytics delivery through various engagement forums: at the Value Evidence Team (VET), Integrated Evidence Team (IET), as part of a study team (in-sourced or out-sourced), and in coordination with the RWDMP team
- Mentor team members, in particular RWA scientists and RW Programmers
**_ Why you?_**:
**Basic Qualifications**:
We are looking for professionals with these required skills to achieve our goals:
- MS in a quantitative discipline such as epidemiology, health economics, health services research, health informatics, or biostatistics
- 3+ years of experience working with RWD for use in pharmacoepidemiology and/or health outcomes research and experience in biostatistics applied to clinical/epidemiological research
- 3+ years of experience and practical knowledge of statistical/analytic software (e.g., SAS, R, IHD)
- Fluency in written and spoken English is required
**Preferred Qualifications**:
If you have the following characteristics, it would be a plus:
- PhD degree in a quantitative discipline such as epidemiology, health economics, health services research, health informatics, or biostatistics
- At least 5 years of experience and practical knowledge of statistical/analytic software (e.g., SAS, R, IHD)
- Prior experience working within the pharmaceutical/biotech industry (preferably in real-world evidence, epidemiology, or health outcomes functional areas)
- Ex
