Principal Biologist, Discovery Research

4 days ago


Cambridge, United Kingdom Hays Specialist Recruitment Limited Full time

Drug Discovery, Biochemical Assays, Mechanisms of Disease Biology, Protein Degradation, Pharmacology
**Your new company**
**Your new role**
- Working to strengthen the development of their novel scientific platform, you will responsible for designing and overseeing project strategies related to characterising in vitro, and ex vivo profiles of lead molecules across the drug discovery portfolio.This involves supporting target validation, lead optimisation and preclinical development of the therapeutic portfolio.
- Utilising your practical understanding of a wide rand of cellular assay technologies (e.g. fluorescence and luminescence end-points in plate-based assays, western blots) and cell line technologies, you will be involved in building out the research capabilitiesof the Biology group, actively working with external collaborators (CROs and academic leaders) in order to address complex scientific questions.

**What you'll need to succeed**
- You will hold a PhD (or equivalent research experience) in Pharmacology, Cell Biology (or related discipline), including proven project leadership experience in an industrial drug discovery environment.
- Utilising your deep understanding of mechanisms of disease biology in one (or more) of oncology, immunology, inflammation or neurological therapeutic areas, you will bring demonstrable experience in molecular and cellular biology techniques applied to thedevelopment of cellular assays, applied to target validation, compound characterisation and screening.
- Some commercial awareness of the targeted protein degradation eco-sphere is an advantage.

If this job isn't quite right for you but you are looking for a new position, please contact us for a confidential discussion on your career.


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