Principal Scientist Discovery Biology
1 week ago
Role Details
Job Title: Principal Scientist Discovery Biology
Location: TRIMTECH therapeutics, The Milner Centre, Cambridge CB2 0AW, UK.
Salary: Competitive salary and benefits package, related to experience & qualifications
Overview
TRIMTECH therapeutics, a rapidly growing well-funded and vibrant early-stage biotech based in Cambridge, UK, is expanding its team. We are seeking a highly skilled and enthusiastic drug discovery scientist to support our efforts. You will have a key role in assay biology, screening, and managing partner collaborations working closely with chemists and external advisors to create transformative new therapeutics.
Join our core team of experienced scientists and drug hunters to develop the next generation of protein degraders, based on the pioneering work of Dr. Leo James and Professor William McEwan (Science, 2024 and Cell, 2024). Our mission is to create novel small molecule degraders of protein aggregates to combat neurodegenerative diseases and address some of society's biggest challenges.
We are seeking a highly skilled, enthusiastic and experienced drug discovery scientist to lead efforts developing and running assays both in the laboratory and with partners. This role will include both laboratory work and management of CRO and partner efforts and bringing together these workflows.
If you are a passionate, experienced scientist looking to make a significant impact in the field of drug discovery, we encourage you to apply to join our dynamic team at TRIMTECH therapeutics. You will be a key contributor to the development of groundbreaking treatments for neurodegenerative diseases.
Specification
Qualifications, Knowledge, and Experience
- Possess a BTEC, BSc, MSc, or PhD or comparable experience.
- At least 5 years in an industrial setting, ideally within a CRO, biotech.
- Hands on experience with high-throughput cellular and biochemical assay development, screening and transfer to other sites or partners.
- Ability to work and manage externally partnered projects at CRO or academic partners.
- A desire to develop drugs and learn new skills.
Essential Skills and Attributes
- Hands on experience with small molecule drug discovery projects.
- Extensive experience with high throughput screening and automation.
- Passion for science and a ‘can-do’ problem-solving approach.
- Excellent interpersonal and communication skills.
- Strong organizational skills, ability to prioritize work internally and at external partners.
- Ability to work with other disciplines such as medicinal chemistry and DMPK experts.
- Ability to develop new assays, SOPs, and transfer them to partners including CROs.
Desirable Skills and Attributes, one or more of these is desirable but not essential
- Expertise with iPSCs and/or neuronal models for drug discovery.
- Experience developing protein degraders.
- Expertise with protein aggregates and their role in disease.
- Understanding of neurodegenerative disease biology.
To apply please send a cover letter and CV to recruitment@trimtechtherapeutics.com
-
Principal Scientist Discovery Biology
1 week ago
Cambridge, United Kingdom TRIMTECH Therapeutics Limited Full timeRole DetailsJob Title: Principal Scientist Discovery BiologyLocation: TRIMTECH therapeutics, The Milner Centre, Cambridge CB2 0AW, UK.Salary: Competitive salary and benefits package, related to experience & qualifications OverviewTRIMTECH therapeutics, a rapidly growing well-funded and vibrant early-stage biotech based in Cambridge, UK,...
-
Principal Scientist Discovery Biology
1 week ago
Cambridge, United Kingdom TRIMTECH Therapeutics Limited Full timeRole DetailsJob Title: Principal Scientist Discovery BiologyLocation: TRIMTECH therapeutics, The Milner Centre, Cambridge CB2 0AW, UK.Salary: Competitive salary and benefits package, related to experience & qualifications OverviewTRIMTECH therapeutics, a rapidly growing well-funded and vibrant early-stage biotech based in Cambridge, UK,...
-
Principal Scientist Discovery Biology
1 week ago
Cambridge, Cambridgeshire, United Kingdom TRIMTECH Therapeutics Limited Full timeRole Details Job Title: Principal Scientist Discovery Biology Location: TRIMTECH therapeutics, The Milner Centre, Cambridge CB2 0AW, UK. Salary: Competitive salary and benefits package, related to experience & qualifications Overview TRIMTECH therapeutics, a rapidly growing well-funded and vibrant early-stage biotech based in Cambridge, UK, is...
-
Principal Scientist, Biology
1 week ago
Cambridge, Cambridgeshire, United Kingdom TRIMTECH Therapeutics Limited Full timePrincipal Scientist Discovery Biology Salary: Competitive salary and benefits package, related to experience & qualifications TRIMTECH therapeutics, a rapidly growing well-funded and vibrant early-stage biotech based in Cambridge, UK, is expanding its team. You will have a key role in assay biology, screening, and managing partner collaborations...
-
Principal Scientist- Mab Discovery
6 hours ago
Cambridge, United Kingdom Reed Scientific Full timeDear [Addressee], REED are working with a world-class life science company to fill a vacancy for an experienced Principal Scientist to join their Antibody Discovery team in Cambridge (UK).In this lab-based role you will be working as part of a team with a particular focuson updating existing processes and implementing state-of-the-art mAb discovery...
-
Molecular Biology Scientist
6 days ago
Cambridge, United Kingdom Hyper Recruitment Solutions Ltd Full timeWe are currently looking for a Molecular Biology Scientist to join a leading Antibody Discovery company based in the Cambridge area. This is a Global Biotechnology company focused on partnering with leading Biopharmaceutical organisation to develop novelAntibodies using their propitiatory Antibody Discovery Platform. Their UK site will focus on the...
-
Scientist - Discovery Screening
3 days ago
Cambridge, United Kingdom TEC PARTNERS LIMITED Full time**Scientist - Discovery Screening - Cambridge** This job role is with an award-winning biotech company in Cambridge that are looking to grow rapidly. They have developed a unique proprietary cellular reprogramming technology that has the potential to be revolutionary in Stem Cell Biology, and the enablingof a new generation of cell therapies. This is a...
-
Early Discovery Scientist
3 days ago
Cambridge, Cambridgeshire, United Kingdom Flagship Pioneering Full timeJob Title: Early Discovery ScientistDescription:We are seeking a highly motivated and goal-oriented Early Discovery Scientist to contribute to and lead Immunology activities across multiple autoimmune-based projects in the early discovery phase.Key Responsibilities:Assess target engagement, in vitro pharmacology, in vivo PK/PD assessment and biomarker plans...
-
Viral Therapeutics Discovery Scientist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Flagship Pioneering Full timeViral Therapeutics Discovery Scientist:Flagship Pioneering is seeking a highly motivated and experienced Viral Therapeutics Discovery Scientist to join our dynamic In Vivo Biology team. As a member of our team, you will be responsible for designing, executing, and analyzing in vivo experiments to evaluate the therapeutic potential of our test articles....
-
Scientist - Cancer Drug Discovery
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Artios Pharma Limited Full timeJoin Artios Pharma Limited, a leading biotech company in the UK, as a Scientist in our cancer drug discovery team. We are seeking an exceptional individual with expertise in cell biology to contribute to our ongoing research projects.About the RoleAs a key member of our team, you will be responsible for creating and running cellular assays to measure the...
-
Senior Drug Discovery Scientist
3 days ago
Cambridge, Cambridgeshire, United Kingdom ZipRecruiter Full timeWe are seeking a Senior Drug Discovery Scientist to join our dynamic team of experienced drug discoverers and target protein degradation experts in a brand-new research facility. This exciting opportunity will give candidates experience of working in a multi-disciplinary team in a drug discovery setting as we advance projects to the clinic.Key...
-
Cambridge, United Kingdom Hays Specialist Recruitment Limited Full timeTranscriptomics, iPSC Culture, Megakaryocytes, Genomics, NGS, CRISPR, Molecular Biology, Platelets **Your new company** As a breakthrough biotech, driven by a group of experienced entrepreneurs who pioneered genome editing, and more specifically brought CRISPR to life, our client is on a mission to utilise their novel cell therapy platform, with the power of...
-
Principal Bioinformatics Scientist
18 hours ago
Cambridge, United Kingdom CK GROUP Full timeCK Group are currently recruiting for a Principal Bioinformatics Scientist to join an early-stage drug development company based in Cambridge on a permanent basis. Hybrid working is available for this role. **The Company**: Our client has built a leading platform for the discovery and development of first-in-class, small molecule drugs that selectively...
-
Principal Research Scientist
2 days ago
Cambridge, United Kingdom Reed Engineering Full timeJob Role:We are seeking a talented Principal Research Scientist - Drug Discovery to join our team in Cambridge. As a senior member of our research team, you will be responsible for driving the drug discovery programs forward using your expertise in computational chemistry, biomolecular structural analysis, and computational modelling techniques.Key...
-
Research Scientist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Artios Pharma Limited Full timeArtios Pharma Limited is seeking a highly skilled Research Scientist to join its world-class research team in the UK. This dynamic role involves contributing biological data to early-stage drug discovery projects, utilizing genetic, cell biological, and pharmacological strategies.Key Responsibilities:Applying expertise in cell and molecular biology to run...
-
Data Scientist for Assay Development
4 days ago
Cambridge, Cambridgeshire, United Kingdom Lightcast Discovery Limited Full timeOur Mission">At Lightcast Discovery Limited, we're dedicated to revolutionizing the field of biotechnology through innovative research and development. Our next-generation microfluidic platform enables precise control over tens of thousands of picolitre volume microdroplets, unlocking new possibilities for scientific discovery.About the Role">This non-lab...
-
Research Scientist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom CV Library Full timeAre you a skilled molecular biologist looking for a challenging role in protein binder discovery? We have an exciting opportunity for a Research Scientist to join our team at Nxera Pharma UK Limited, based in Granta Park, Cambridge.About the CompanyNxera Pharma is a technology-powered biopharma company dedicated to developing new specialty medicines to...
-
Principal Scientist
6 days ago
Cambridge, United Kingdom CY Partners Full time**Principal Scientist - Protein Expression** **Cambridgeshire Based** **£60,000 - £75,000 + Bonus + Excellent Benefits** Are you an expert in using insect cell culture for protein/enzyme production? Would you like to work for an exciting early-stage biotechnology company, supporting their novel assay platforms? My client is a Cambridge based...
-
Cambridge, United Kingdom Hays Specialist Recruitment Limited Full timeAntibody Discovery, Immuno-Oncology, Biochemistry, Mammalian Cell-Based Assays **Your new company** IPO pioneers in immunotherapies (immuno-oncology), including heat shock protein-based cancer vaccines, this exciting biotech is relentless on their goal to treat cancers with novel combinations, utilising their next-generation portfolio of checkpoint...
-
Principal Scientist
6 hours ago
Cambridge, United Kingdom TEC PARTNERS LIMITED Full timeTEC partners are working with a rapidly growing company that provides instruments and specialist consumables for the global pharmaceutical and academic research community. Their novel single cell analysis systems can lead to a life-changing medicine. Based in Cambridge as Principal Scientist you will have the opportunity to develop technology that enables...