Bmt & Cellular Therapies Fellow

2 weeks ago


Sutton, United Kingdom The Royal Marsden NHS Foundation Trust Full time

Cellular Therapies and Haematopoetic Stem Cell Transplant Clinical Fellow

0.8WTE

12 Months Fixed Term Contract

This is an exciting post in the Department of Haemato-Oncology at Royal Marsden Hospital as a clinical fellow in Cellular Therapies and Haematopoetic Stem Cell Transplant (HSCT). This post would be suitable for a haematology trainee with an interest in Cell Therapies and HSCT.

This post is for 12 months and is a 0.8WTE post with time split equally between Cell Therapy and HSCT. In addition this will require the post holder to work in both RMH Sutton and RMH Chelsea. It is expected that the post holder will contribute to the on-call out of hours service.

The post holder will be involved in the care of patients undergoing treatment with CAR-T Cells for NHL, B-ALL and Myeloma and other cellular therapies being delivered as part of clinical trials. They will gain experience in patient selection and assessment, bridging therapy, lymphodepletion and infusion and management of acute and long term complications of CAR-T cell therapy. In addition the post holder will be involved in care of patients pre and post allogeneic and autologous HSCT and will gain experience in pre transplant assessment and work up and conditioning regimens, management of infectious complications, Graft versus host disease and late effects of transplant.

The post holder will be working alongside a HSCT coordinator (medical) and Cell Therapy fellow. In addition they will work closely with nursing coordinators and specialist nurses and the Cell Therapy/HSCT consultant team.

There is a well-established JACIE accredited haematopoietic stem cell transplant and cell therapy programme. We have a team of 4 pre-transplant CNS’ and 2 post-transplant CNS’. In addition to adult transplants we also care for the teenage and young adult population (ages 18-25 years).

There is an active, innovative, Palliative Care and Symptom Control Service led by a dedicated Consultant in Palliative Care, providing twenty-four-hour advice and care and linking with a local Hospice.

The Royal Marsden’s Haemato-oncology Unit is one of the largest in Europe, diagnosing, treating and researching blood cancers in adults and children. The unit runs over 60 clinical trials at any one time and is one of the largest stem cell transplant units in the UK, offering all forms of transplant in both children and adults, as well as various forms of immunotherapy.

The unit performs HSCT on a wide range of blood cancers including multiple myeloma, acute myeloid leukaemia, myelodysplastic syndrome, acute lymphoblastic leukaemia, myelofibrosis and lymphoma (Hodgkin and non-Hodgkin). We perform approximately 150 autologous and 70 allogeneic stem cell transplants a year. Within the allogeneic transplants we perform a high number of transplants using alternative donors including cord blood and haploidentical donors. In addition, we also perform around 10 autografts per year for germ cell tumours. We have been treating patients with chimeric antigen receptor T cells since 2019 and have infused more than 60 patients since then.

The Unit is currently involved in multi-centre national and international trials evaluating new therapeutic strategies. The research activities of the clinical Unit are closely integrated with the Divisions of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research.

Please refer to the attached job description/person specification for a more thorough breakdown of the role.



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