Early Phase Clinical Research Fellow

4 weeks ago


Liverpool, United Kingdom The Clatterbridge Cancer Centre NHS Foundation Trust Full time

This post is a full time appointment for an initial period of 12 months with potential to extend to 24 months. The role to provide medical support to the Early Phase Trials team including consultants, nursing and administration staff by primarily acting as co-investigator on early phase clinical trials. The successful applicant will join a highly motivated and empowered workforce to increase research capacity and deliver innovative early phase research in compliance with Good Clinical Practice (ICH-GCP) and Trust policy.

This is a 10 session non-training post funded through The Clatterbridge Cancer Centre for an initial period of 1 year (potential to extend to 2 years). The Early Phase Clinical Research Fellow role is suitable for individuals towards the end of, or having completed, their specialist oncology training who wish to gain further experience in experimental medicine and Phase I trials, including first-in-human trials, clinical pharmacology trials and transnational research.

The position requires an ability to understand and deliver early phase clinical research, liaising across a range of clinical, academic and administrative staff throughout the Trust and with external organisations (pharmaceutical and biotech industry partners, academic institutions and other hospitals).

The post-holder will participate in a diverse range of clinical research trials as a co-/sub-investigator and manage all aspects of trial patients. The appointee is required to attend 6 trial outpatient clinics per week, Safety Review Committee meetings to discuss trial patients, molecular tumour board meetings and wait list meetings to discuss trial patients and to agree opportunities for patients to enrol in early phase trials.

The post-holder will undertake the administrative duties associated with the care of their patients. The role also involves presenting research work, being involved in the development and delivery of audits, writing papers and reviews and participating in all relevant aspects of clinical governance, under the supervision of the other consultants in the Early Phase Trials team.

The Trust supports the requirements for continuing a level of continuing professional development consistent with the recommendations of the Royal College of Physicians. Appropriate arrangements for study leave will be made in conjunction with colleagues.

The Clatterbridge Cancer Centre is one of three specialist cancer centres in England. With 1,700 staff and three sites, we are one of the largest NHS providers of non-surgical cancer treatment. The Trust serves the 2.4 million population across Cheshire & Merseyside and is consistently rated by patients as one of the best performing hospitals.

We opened Clatterbridge Cancer Centre - Liverpool (CCC-L) in June 2020, enabling us to work more closely with clinical colleagues in the neighbouring acute hospital, to support our sickest patients. This state-of-the-art flagship cancer hospital, along with our sites in Wirral and Aintree means we are able to provide care closer to home for cancer patients across Cheshire & Merseyside. The new hospital is based in the heart of Liverpool’s Knowledge Quarter enabling us to expand our cancer research programme alongside our academic partner, the University of Liverpool.

We are a tertiary cancer centre, providing non-surgical cancer care. Our reputation and specialist services attract national and international cancer patients. We have a unique multi-site care model consisting of three main sites, four additional systemic anti-cancer therapy (SACT) sites and 15 outpatient centres, making us one of the largest NHS providers of non-surgical cancer treatment for solid tumours and blood cancers. Our clinical model also includes the provision of chemotherapy in the home and workplace.

**Research**: A diverse range of clinical research trials are in progress and, following training, you will be expected to participate in these studies as a co-/sub-investigator. These include Phase I trials of immunotherapeutics, small molecule inhibitors, next-generation chemotherapy trials, combination / multi-modality Phase I trials, molecular characterisation / translational studies. In addition to the research projects outlined above, the post-holder may be involved with new patient consultation, consent and screening, and reviewing patients at follow-up appointments.

Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 6 trial outpatient clinics per week (see indicative timetable).

**Protocols**: You will be expected to undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to harness opportunities to be involved in the development and planning of new studies.

**Professional Development**: You will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians



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