Research Scientist

4 weeks ago


United Kingdom Earlham Institute Full time

You will need to download, save and complete a copy of the application form using Microsoft Word or preparea copy of your CV that contains all the information requested in the application form.
Applications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK.
In humans, over 90% of the variants associated with traits are found within noncoding regions of the genomes, either within genes' introns, untranslated regions, promoters, or within intergenic regulatory regions such as enhancers.
As such, depending on the genetic disorder, between 30% and 70% of the patients do not receive a genetic diagnosis as the likely causative variants fall outside coding sequences.
As part of this highly collaborative project bringing together computer scientists, data scientists, bioinformaticians, clinicians across academia and industry, we are seeking an enthusiastic and ambitious postdoctoral research scientist to undertake computational analysis of the functional implications of variation within noncoding functional sequences in relation to cardiovascular disorders.
As part of the EU Horizon / Innovate UK funded project “Next Generation Tools for Genome-Centric Multimodal Data Integration in Personalised Cardiovascular Medicine” , the role will engage with primary research.
The post holder will work closely with external partners and members of the EU consortium, and will focus on developing machine learning applications to investigate the implications of genetic variation within noncoding functional elements in relation to cardiovascular disorders.
The post holder will lead on the development and testing to applications to identify noncoding functional elements based on integration of multi-omic data (genome, transcriptome, epigenome) and integrate this novel information in the development of tissue / condition specific regulatory network, with the aim of prioritising variants occurring within those regions based on their predicted impact. They will also lead on the analysis, preparation, and submission of the associated manuscripts.
The successful candidate will develop computational pipelines centered on machine learning applications such as convolutional neural network to reproducibly handle multi-omic data (genome, transcriptome, epigenome) to enable functional sequence annotation, network reconstruction, and the interpretation of the implication of genetic variation within those disorders.
The post holder will have access to cutting-edge high performance computing facilities and expertise. They will join an active community of experimental and computational biologists working on a wide range of genomics analyses. They will also have the opportunity to contribute to other projects at EI.
The successful applicant will have a PhD in bioinformatics, computational genomics or a related subject.
They will have significant experience working with genomic/epigenomic/transcriptomic data, and experience with machine learning applications in genomics investigations. The candidate should have a demonstrable working knowledge of programming languages such as Python, Perl, or R.
Salary on appointment will be within the range £35,300 to £43,750 per annum depending on qualifications and experience. This is a full-time post until 31 December 2027, with a possibility of a 6-month extension.
This role meets the criteria for a visa application, and we encourage all qualified candidates to apply. Please contact the Human Resources Team if you have any questions regarding your application or visa options.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.


  • Research Scientist

    1 month ago


    United Kingdom Diageo España SA Full time

    Aarti Calvin | Video | Careers | Diageo plc Meet our People: Aarti Calvin, Senior Liquid Scientist, GB 15 Jan 2023 Hear from Aarti Calvin, a Senior Liquid Scientist within Diageo's European Innovation Research & Development (R&D) team. #J-18808-Ljbffr

  • Research Scientist

    1 month ago


    United Kingdom Cranleigh Scientific Ltd Full time

    A groundbreaking start-up working on novel DNA/RNA sequencing technology is recruiting a Research Scientist to join its team based in Edinburgh on a permanent basis. The company has just closed out their pre-series A funding round and is investing heavily in all areas of its team as it looks to release its product for clinical studies. You will play a...

  • Research Scientist

    1 month ago


    United Kingdom Amazon Full time

    Job ID: 2588378 | Evi Technologies Limited Our team undertakes research together with multiple organizations to advance the state-of-the-art in speech technologies. We not only work on giving Alexa, the ground-breaking service that powers Echo, her voice, but we also develop cutting-edge technologies with Amazon Studios, the provider of original content...


  • United Kingdom MMR Research Full time

    Or, are you a Graduate looking to kick start your journey in stats? We are open to bringing on board either a Junior Statistician or someone who has a 1-2 years experience and is looking for the next step in their career. MMR is an independent, global consumer and sensory research agency specialising in food, drink, personal and household care research....

  • Research Scientist

    2 weeks ago


    United Kingdom Certara Full time

    Overview We have an immediate opening for a Research Scientist / Senior Research scientist with a background in paediatric Pharmacokinetics. The candidate should have working familiarity wit h physiologically based pharmacokinetic modelling. The successful candidate will join an internationally recognised, multidisciplinary research team, providing...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Research Associate Scientist/Scientist I Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. customer base who access our comprehensive suite of drug discovery services; medicinal chemistry screening support,...


  • United Kingdom Instil Bio, Inc. Full time

    Would you like to apply your expertise to the development and manufacture of life changing medicines in a company that follows the science to achieve life changing outcomes to cancer patients? Instil Bio is a science driven dynamic cell therapy company on the frontier of revolutionising cancer treatment. We are changing the course of medicine, drawing on our...


  • United Kingdom Advance Africa Ltd Full time

    KEMRI Principal Clinical Research Scientist Jobs in Kenya KEMRI Principal Clinical Research Scientist Jobs in Kenya KEMRI Principal Clinical Research Scientist Jobs in Kenya KEMRI Principal Clinical Research Scientist Jobs in Kenya The officer will be based at the Malaria Division of KEMRI’s Centre for Global Health Research in Kisumu, western...

  • Research Scientist

    1 month ago


    United Kingdom BioIndustry Association Full time

    BioDivide Limited is a cell therapy and advanced biologics company with laboratories based in the South-West, United Kingdom. They are hiring a full-time Research Scientist to support research and process development. Role overview You will carry out a range of research-related and process development activities as well as maintain both GMP-regulated and...

  • Research Scientist

    1 month ago


    United Kingdom National Physical Laboratory Full time

    In doing so, the National Physical Laboratory is helping to combat issues on a global scale such as climate change, curing diseases, and the development of cutting-edge communications technology. Our role is to research, create and deliver the measurement infrastructure which underpins the UK's prosperity and quality of life across many fields of industry. ...


  • United Kingdom Metrion Biosciences Ltd. Full time

    Research Associate Scientist/Scientist I About Metrion Biosciences Metrion Biosciences (‘Metrion’) is a UK-based, ion channel focused Contract Research Organisation (CRO) providing high-quality in vitro preclinical drug discovery and safety profiling services. Formed in 2015, Metrion has since established a loyal and growing global customer base who...

  • Research Scientist

    2 weeks ago


    United Kingdom Oxford Nanopore Technologies Ltd. Full time

    Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe. Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics,...

  • Research Scientist

    3 weeks ago


    United Kingdom The Earlham Institute Full time

    Hours per week 37 Project Title Next generation tools for genome-centric multimodal data integration in personalised cardiovascular medicine Months Duration 48 As part of the EU Horizon / Innovate UK funded project “Next Generation Tools for Genome-Centric Multimodal Data Integration in Personalised Cardiovascular Medicine”, the role will engage with...

  • Research Scientist

    4 weeks ago


    United Kingdom Kromek Group plc Full time

    We are seeking a highly skilled and experienced Principal Scientist to lead our research and development efforts in Biotechnology. The Principal Scientist will be responsible for designing and executing research projects, analysing data, and providing scientific expertise and leadership to the research team We are seeking a highly skilled and experienced...


  • United Kingdom taylorollinson Ltd Full time

    Permanent opportunity offering competitive salary, based on experience. Due to continued success, our client is now seeking an experienced Senior Scientist to undertake a new role within their Molecular Biology team. Working alongside a small research team, the role requires the individual to take ownership of research projects, and utilise their...


  • United Kingdom Centre People Full time

    A fast-growing biotech start-up is looking for a Higher Scientist or Scientist to join their research team in London and Manchester. The company’s focus is on technological development of reproductive cells with iPS and ES cells. This is an amazing opportunity for those looking to join the commercial industry from academia and wishing to continue to...


  • United Kingdom The Earlham Institute Full time

    Hours per week 37 Project Title Next generation tools for genome-centric multimodal data integration in personalised cardiovascular medicine Months Duration 48 Job Description Main Purpose of the Job As part of the EU Horizon / Innovate UK funded project “Next Generation Tools for Genome-Centric Multimodal Data Integration in Personalised...


  • United Kingdom Lonza Biologics Porriño SLU Full time

    Here at Lonza we have a great opportunity available for a Scientist to join our Research & Development department. This is a permanent position based out of our Cambridge facility. The role also involves leading multiple client projects as well as developing current and new bioassays platforms. Bachelor Degree in Biological Sciences/Immunology/Bioassay...


  • United Kingdom Earlham Institute Full time

    You will need to download, save and complete a copy of the application form using Microsoft Word or preparea copy of your CV that contains all the information requested in the application form. Applications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK. Background: ...


  • United Kingdom Centre People Full time

    A fast-growing biotech start-up is looking for a Higher Scientist or Scientist to join their research team in London and Manchester. The company’s focus is on technological development of reproductive cells with iPS and ES cells. This is an amazing opportunity for those looking to join the commercial industry from academia and wishing to continue to...