Bioinformatician/Senior Bioinformatician

2 weeks ago

United Kingdom GenomeWeb LLC Full time

Monthly salary starting at £2,738.29 after tax + other paid benefits

  • 30 days annual leave per year plus 8 bank holidays
  • Annual salary review
  • Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)
  • Death benefit, long-term care, accident at work and unemployment insurances
  • Relocation package including installation grant (if required)
  • Extensive sports and social club activities (run on campus and remotely)
  • Family benefits : Onsite nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances
  • Benefits for non UK residents: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance
Job Description

We are looking to recruit an enthusiastic Bioinformatician to work in the Genetic Data Platform group that is delivering EMBL-EBI’s role in the AMP-T2D Knowledge Portal and the INTERVENE project, addressing human genetic variation data in common diseases and using this data for the calculation of polygenic risk scores.

The AMP-T2D Knowledge Portal aims to make T2D-relevant genetic association data more easily accessible. The portal draws genetic associations and functional genomic data from a federated database with nodes at the Broad Institute Data Coordinating Center (DCC), the European Bioinformatics Institute (EBI), and the University of California San Diego (UCSD). It provides access to these data through application programmatic interfaces (APIs) and a web-portal with visualizations built by the Broad and the University of Michigan (UM). The network of scientists who contribute data or methods to the portal is managed through protocols developed by the DCC. The portal has >20,000 users worldwide and contains data from >80 studies for >180 T2D-relevant traits.

The INTERVENE consortium is a 5-year EU funded project that aims to develop and test next generation tools for disease prevention, diagnosis and personalised treatment utilizing the first US-European pool of genomic and health data and integrating longitudinal and disease-relevant -omics data into genetic risk scores. INTERVENE will build a new European platform that will allow researchers and clinicians to easily calculate genetic scores with the goal to enable a wide adoption of genetic risk scores as a gold standard in clinical research. EMBL-EBI’s role is to deliver this federated platform and to integrate this with controlled access datasets.

The successful applicant will work in a group of Bioinformaticians and Software Developers to deliver EMBL-EBI's contributions to these projects. The team collaborates closely with the NHGRI-EBI GWAS Catalog, the Polygenic Score Catalog (a collaboration between University of Cambridge and EMBL-EBI), and the Broad Institute. Requirements You have
  • A postgraduate degree in the life sciences or similar, or equivalent industry experience
  • Experience acquiring and analysing complex disease human genetic and phenotypic data from arrays, WES and/or WGS, preferably in a bioinformatics
  • service or research environment in academia or industry.
  • Experience of using a computer scripting language (e.g. python, Perl etc.)
  • Experience in contributing to complex projects across a team or a number of partners
  • Excellent written and verbal English language skills
  • A high level of accuracy and attention to detail
  • Good organisational skills, the ability to prioritise different tasks and to manage a heavy workload for collaborative projects
  • A proven ability to effectively interact with multiple stakeholders to deliver results
  • Excellent interpersonal and communication skills
  • A high level of independent working, initiative, and flexibility to changing tasks
You might also have
  • Experience of interacting with relational databases to extract reporting information
  • Familiarity with commonly used ontologies for human phenotypes
  • We operate an agile software development environment, therefore experience of agile software delivery is preferred
  • Experience with ML/AI techniques and data preparation to enable these analyses
How to Apply What else you need to know

This position is project-limited for an initial 3 year duration (or until end 2025).

To apply please submit a covering letter and CV through our online system.

At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ and individuals from all nationalities. Visa exemptions will be offered tointernational candidates and details will be discussed during interview. We believe in science without borders and thiscontinues after Brexit .

This role is based inHinxton, UK and you will be required to relocate once it is safe to do so if you are currently based abroad or not within commuting distance. More info on how we are recruiting in this period is available on our page:Recruitment and Onboarding during Covid19 .

We aim to provide a response within two weeks after the closing date.

Job no.: EBI01820 About Our Organization

EMBL-EBI is a worldwide leader in bioinformatics. We encourage personal and professional development and are committed to ensuring our employees feel valued, supported and empowered to reach their potential at work.

Science Careers writes that graduate students in the US and Canada are pushing for better wages.

A poll finds that more than quarter of women in academia think they were not promoted because of their gender, according to the Chronicle of Higher Education.

Nature News reports that university employees in the UK went on strike this week to protest pension cuts and more.

Inside Higher Ed reports that after years of negotiation, Columbia University and student-workers there have reached a contract agreement.

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