Senior Manager, Commercial Supply Chain
3 weeks ago
Full details of the job.
Vacancy Name
Vacancy Name Senior Manager, Commercial Supply Chain
Vacancy No
Vacancy No VN238
Employment Type
Employment Type Permanent
Location of role
Location of role Abingdon
About the Company
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases. We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. You will work with outstanding people who together pioneer the research, development and commercialization of bi-specific TCR therapies. We aim to create an environment where individual contributions and initiatives can be maximized, while fostering a culture of collaboration, based on respect and integrity. We want each individual employee to own their career, as part of high-performing teams, and in the context of on-the-job and formal continuous development and training, as well as constructive feedback. We always strive to identify ways to improve what we do and how we do it, by asking questions, voicing opinions, exploring various approaches and staying connected with healthcare professionals, patients, academia and other key partners.Key Responsibilities
Key Responsibilities MAIN PURPOSE OF JOB
The Senior Manager of Commercial Supply Chain reports to the Director, Global Commercial Supply Chain and is responsible for supporting commercial third-party logistics (3PL) supply chain operations for Immunocore. Through strategic planning, management, and co-ordination of management of external suppliers, CMO and 3PL providers, manufacturing of Finished Product (packaging and labelling), warehousing, inventory management/ERP, shelf-life management, global distribution to third-party specialty and wholesale distributors, shipping & customs, ensuring the timely and cost-effective delivery of commercial supplies to medical centres and patients. Working in partnership with Immunocore colleagues in CMC, Regulatory, Quality Assurance, Clinical Operations, Medical Affairs, Commercial & finance, as well as with external vendors and 3PL providers. KEY RESPONSIBILITIES• Ensuring the logistical, compliance and regulatory integrity of Supply Chain activities to enable progression of Commercial activities.
• Support an expanding Supply Chain organisation. This position will support the following functional Supply Chain areas:
- Third Party Logistics & Warehousing
- Inventory management
- Supporting ERP implementation
- Production of Finished Product (Packaging and Labelling) and support serialisation
- Demand & Supply Planning S&OP. Project managing, Integrated Business Planning (IBP) process within business, working together with finance, commercial, supply chain, Manufacturing & outsourcing.
- Shelf-life management
- Global distribution to third-party specialty and wholesale distributors.
- Supporting Immunocore commercial partner (e.g., Central East European countries, AU, Israel, and South America)
- Shipping & Customs
- Authorship commercial supply chain compliance documents (i.e., SOP, Work Instruction, change management, deviation/none-conformance)
- Reviewer of distribution and quality technical contracts
• Working with CMC manufacturing, Clinical Operations, Commercial, Finance, Regulatory Affairs and Quality Assurance to produce processes that are robust, efficient, and cost effective, ensuring the timely and cost-effective delivery of commercial supplies to medical centres and patients.
• Develop supply chain options, facilitate decision-making, and communicate updated manufacturing and commercial supply plans to all impacted stakeholders.
• Fully conversant with philosophies and regulatory guidelines pertinent to Commercial Supply Chain. Contribute and manage the relevant supply chain information included within regulatory submissions (e.g., IND, IMPD, BLA, MAA)
• Collaborate with IT to develop and implement supply chain IT systems and tools for Supply Chain planning, execution, and analysis.
• Proactively identify and resolve Supply Chain problems/barriers. This behaviour requires lateral independent thinking and innovative generation of ideas and solutions, coupled with an awareness of the appropriate compliance and regulatory environment.
• Support effective resource management and control of annual Commercial Supply Chain budgets. Plan, develop and deploy resources and budget plans and meet agreed spending targets.
Other
• Contribute to Immunocore governance bodies and Program teams to progress drug candidates through lead selection/optimization, preclinical development, clinical development and through to commercial life cycle management.
• Communicate effectively and transparently with functional heads within Research, Development and Commercial across the company.
• Facilitate a suitable Health & Safety working environment for employees.
• Work with QA to develop and maintain a fit-for-purpose Quality Management System for Supply Chain, suitable of supporting regulatory inspections.
• Involved in Wholesale Distribution Activities and must be trained and understand the requirements of Good Distribution Practices as defined in Directive 2001/83/EC and various national legislations.
• Must have regular and continual training relevant to the role of Associate Director of Global Commercial Supply & Distribution. Training will include specific aspects of product identification and avoidance of falsified medicines entering the supply chain. PERSON SPECIFICATION EXPERIENCE AND KNOWLEDGE Essential
• Minimum of 3 - 5 years of progressive Supply Chain management and experience within pharmaceutical industry
• Breadth of Supply Chain management experience, including supply planning and procurement
• Experience working with Contract Manufacturing/External Supply Management
• Experience with commercial pharmaceutical/biotech company supply chains preferred.
• Strong background of working with ERP/MRP/Supply Chain systems and tools
• Excellent supply chain analysis skills (e.g. modelling, “What If” analysis)
• Strong relationship building skills
• GxP experience Desirable
• Contributed to CMC Module 3 regulatory sections
• Proven track record of line management and building a department
• Working knowledge of finance and budgeting
• Familiar with QA and Regulatory working practices EDUCATION & QUALIFICATIONS • Essential: BSc. or MSc. in business, supply chain operations or related discipline
• Desirable: PhD in related discipline #J-18808-Ljbffr
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