Senior Scientist Bioscience Renal in vivo

Are you ready to turn ideas into life-changing medicines At AstraZeneca we are driven by the potential of science to address unmet patient needs globally. Our vision is to push the boundaries of science redefining the practice of medicine and ultimately eliminating diseases like cancer respiratory cardiovascular and renal conditions. Join our Animal Sciences & Technologies (AST) Department in Cambridge where we conduct pivotal studies to evaluate drug efficacy safety and pharmacokinetics. Use your expertise to collaborate with disease-focused teams and support the growth of our drug portfolio. This vivarium-based role is detailed for professionals experienced in animal work who thrive in fast-paced collaborative environments.Are you a guide in vivo biologist with excellent in vivo experimental skills and outstanding understanding of animal handling and care Would you like to apply your expertise in a company that pushes the boundaries of science to turn ideas into life changing medicines Join us to discover future treatment ofRenal diseasesIntroduction to role:At AstraZeneca we are led by science and driven by patients. Its at the heart of our every success. That is only possible when we all work together well always make sure youre clear about how your role is connected to our wider mission to really show what science can do.We are now recruiting a Senior Scientist with knowledge in in vivo experimental biology to join the Bioscience Renal in vivo team within the Early Cardiovascular Renal and Metabolism (CVRM) therapeutic area. The position is placed at AstraZenecas vibrant R&D site in Cambridge UK. As a Senior Scientist in the Early CVRM Renal department at AstraZeneca you will be part of a vibrant team that focuses on finding new treatment options for patients with renal the in vivo team we work with various pre-clinical models and different drug modalities. You will conduct experimental studies develop renal in vivo models and perform biomarker analysis to drive our targets. At AstraZeneca you will work together with experts from different functions and be part of project teams.Accountabilities:As a Senior Scientist in the Renal in vivo team you will:Independently develop plan and perform high quality in vivo experiments in rodent models of renal diseaseInvestigate MoAPerform Ex vivo analyses of fluids and tissue for biomarker quantificationIdentify and implement new models/assays relevant for renal disease areaAct as Bioscience representative in projectsAnalyse and deliver data presentations reports and regulatory documents in a timely mannerEnsure that own work and work with others is performed according with appropriate safety health and environment (SHE) qualify and compliance standards e.g. General Laboratory Standard (GLS).Essential Skills/Experience:Experienced hands on in vivo biologist with a PhD or equivalent experience (or MSc with 3 years or BS with 5 years in vivo experience in industry or academic setting) with in biology physiology pathology or medicine or other relevant areaExtensive expertise in running in vivo experiments in rodentsExcellent experimental skills in the use of in vivo techniques and good understanding of practice of animal handling and careEx vivo in vitro techniques - qPCR ELISAs etcFlexibility & independenceEducated and certified for in vivo experimentationStrong oral and written communication skills in EnglishDesirable Skills/Experience:Holder of UK Home Office Personal LicenceExperience in renal modelsExperience in biomarker identification in body fluids and tissuesExpertise in renal physiology and/or pathologyExperience from Pharmaceutical industrySo whats nextAre you already envisioning yourself joining our team Good because we cant wait to hear from youTo find out more:Group site: social media Follow us on LinkedIn: AstraZenecaInclusion & Diversity: site: Posted07-out.-2025Closing Date20-out.-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:Senior IC Key Skills Laboratory Experience,Mammalian Cell Culture,Biochemistry,Assays,Protein Purification,Research Experience,Next Generation Sequencing,Research & Development,cGMP,Cell Culture,Molecular Biology,Flow Cytometry Employment Type : Full-Time Experience: years Vacancy: 1