Associate Principal Scientist for The Renal

15 hours ago

Cambridge, United Kingdom AstraZeneca Full time

**Associate Principal Scientist for the Renal bioscience In-Vitro team - CVRM**

**Location: Cambridge, UK**

At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

We are now recruiting an **Associate Principal Scientist **to join the Bioscience Renal in-vitro team within the Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area. The position is placed at AstraZeneca’s vibrant R&D site in **Cambridge, UK. **The group are moving to the Cambridge Biomedical Campus from the end of November.

You will be part of a vibrant Renal Bioscience Department that focuses on finding new treatment options to people living with renal disease. In the in-vitro team we work with various in vitro models and different drug modalities. You will take part in establishing and developing new methods, models, biomarker analysis, driving new targets, and being part of drug project teams. You will be required to show scientific leadership in renal areas and have the possibility to present data internally and externally as well as writing manuscripts for publication. At AstraZeneca, you will collaborate with experts from different functions.

CVRM is one of AstraZeneca´s core therapy areas and renal disease is one of AstraZeneca’s strategic research areas within CVRM that aims towards new treatments to halt, slow or reverse the progression of kidney disease.

**What you’ll do**

With a passion for science, you will support our growing portfolio in the renal disease area by joining a team of professionals who are passionate about advancing science to discover and develop novel therapeutics that will benefit kidney patients.

Main duties and responsibilities
- Deliver & analyse data, provide interpretations using scientific rigor from own data and that of others, and prepare presentations, reports, regulatory documents in timely manner
- Work collaboratively with project teams, CROs, and academic partners to define the in-vitro strategy and support early drug discovery programs
- Identify and develop new target ideas, implement new models/assays/ latest technologies relevant to the renal disease area
- You will work independently and will be encouraged to plan your daily work in collaboration with your team leader
- Show scientific leadership by presenting work at internal and external meetings, write scientific publications and presentation of original work at scientific conferences and symposia

**Essential for the role**
- Hands-on expertise in setting up, validating, and running in-vitro models of kidney diseases including complex 3D models
- PhD in pharmacology, physiology or medicine or other relevant area
- Enthusiasm for laboratory work and experience in lab analytical techniques such RT-qPCR, ELISA, WB, as well as extensive experience in data QC, analysis, interpretation
- Ability to work as part of a team to achieve a common goal and work with multiple projects concurrently
- Hard working, organised, balanced and meticulous with an ability to perform under pressure
- Provide solutions to a variety of problems of diverse scope involving basic scientific principles

**Desirable requirements**
- Good understanding of drug development process with a demonstrable experience in industry/biotech drug discovery

**So, what’s next?**

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you

**Where can I find out more?

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