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Senior / Principal Scientist, Target Validation & Tractability
3 months ago
Make your mark for patients
About the role
The position is a lab-based role, requiring excellent laboratory skills, particularly on molecular and cell biology techniques. The position is a lab-based role, requiring excellent laboratory skills, particularly in cell biology/assay techniques. Additionally, we are looking for experience with creating and analysing '-omic' datasets, practical experience of bioinformatic techniques and basic coding skills would be advantageous.
Who you'll work with
The successful candidate will be part of a multi-disciplinary team, focusing on the discovery and validation of novel drug targets for diseases with high unmet patient need.
What you'll do
- Studying immunological disease pathways and biology, to generate novel insights into potential therapeutic opportunities in areas of unmet need.
- Setting up new and running new collaborations with state-of the-art researchers on auto-immune relevant biological pathways and disease models with the aim of identifying new disease-drug target links.
- Performing drug tractability and validation experiments, such as Gain of Function /Loss of Function assays, cell culture, flow cytometry, imaging, and other techniques. Generating and critically assessing data to support go/no-go new target decisions.
- Contribute to the development of the technological and scientific acumen of the department, helping to enhance our target to disease translational insights, implementing novel technologies, improving workflows and robust scientific discussion
- Present data and insights across the organization and externally
- Work in a collaborative, matrix style right across the organisation to implement the adoption of new targets into the research portfolio.
- Produce detailed experimental write-ups and assist in producing and collating procedures, guidelines and reports.
Interested? For this role we're looking for the following education, experience and skills
- Educated to degree level with industry experience, PhD desirable.
- Experience in a range of cellular and molecular biology techniques – for example: cell culture, flow cytometry, high content imaging, ELISA or MSD, Western blotting, qPCR, cloning, transfection/siRNA/CRISPR gene-editing.
- Experience with bioinformatic tools for analysing large NGS/'omic' datasets and basic coding skills
- Good communication skills and comfortable presenting experimental data at cross-functional meetings.
- Knowledge of coding is advantageous.
- Experience with use of bioinformatic tools to visualise and curate from large datasets.
- Ability to work within a team in a fast-paced environment with changing priorities.
- Highly motivated and driven to exceed goals.
Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you
About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.
Why work with us?
At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.
UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA- Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
