PhD Studentship: Unravelling the Role of Genotoxic E. Coli in Colorectal Cancer

Primary supervisor - Dr Fred Warren The infant gut is a complex, constantly adapting ecosystem which shows distinct shifts as a consequence of introducing solid foods, which can have lifelong health impacts. An important nutrient in weaning foods is starch, a key dietary component in the adult diet. The genus Bifidobacterium has several adaptations making it...

Primary Supervisor: Dr James Smith Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. During development, cardiomyocytes withdraw from the cell-cycle and switch from proliferative, growth to non-proliferative, hypertrophic growth. It is becoming clear that the extracellular matrix molecules play a key role...

Primary supervisor - Dr Myriam Charpentier Nitrogen (N) acquisition is fundamental for plant growth. However, N is poorly available in soils, leading to extensive and costly chemical fertiliser applications. It is estimated that 50-70% of nitrogen-derived fertilizer provided to the soil is lost, giving rise to soil and water pollution as well as global...

Primary Supervisor: Dr. Rebecca Taylor Ageing is associated with increased rates of disease, including neurodegenerative conditions. Prion-like proteins (PrLPs) play major roles in age-associated neurodegeneration, but their physiological functions are often poorly understood. Defining these functions would increase our understanding of the behaviour and...

Primary supervisor - Dr Dmitry Ghilarov BackgroundThe acute problem of antimicrobial resistance incentivises us to develop innovative approaches to antibiotic discovery & production. Natural products that form the basis of our current medical arsenal are often difficult to synthesize, purify, or engineer. In recent years bioinformatically predicted peptide...

Primary supervisor - Professor Martin Warren This PhD opportunity is ideal for graduates in biochemistry or biomedical science with a keen interest in protein science and its application in developing new diagnostic tests and assays. Recently, the National Institute for Health and Care Excellence (NICE) issued comprehensive guidelines on diagnosing and...

Primary supervisor - Professor Diane Saunders Wheat blast and rusts are fungal diseases that severely damage cereal production worldwide. During infection, these fungi secrete proteins into wheat plants to reprogramme host plant circuitry, supporting their own growth and development. A subset of effectors, termed avirulence factors (Avr), can be recognised...

Primary supervisor - Professor Antony Dodd Climate change poses a significant threat to our food supply, but you can be part of the solution In this groundbreaking research project, we're investigating how plants adapt to changing seasons and temperatures, with a focus on ensuring robust crop production despite environmental challenges.You'll explore the...

Primary Supervisor: Dr Rianne Lord Bacterial infections are the second-leading cause of deaths globally, and whilst antibiotics have undoubtedly saved millions of lives, their extensive use, coupled with pathogen evolution has resulted in drastic increases in prevalence of antibiotic-resistant strains. Amongst these, Gram-negative pathogens pose the most...

Primary Supervisor: Professor Andrea Münsterberg Segmentation of the main body axis is a fundamental and conserved feature of all vertebrate embryos. It results in the metameric organization of the vertebral column and its associated muscles, nerves, and blood vessels. The vertebral column is produced by somites, transient aggregates of cells generated by...

Primary supervisor - Dr Andrew Gates As well as carbon dioxide (CO2), other important climate-active gases are known to drive global warming. Importantly, nitrous oxide (N2O), is the third most abundant greenhouse gas with 300-times greater global warming power than CO2 and it also contributes to the destruction of the ozone layer. Production of N2O is a...

Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Little is known about how GBS resists the immune system and colonises to cause invasive disease. This PhD will develop a new understanding of how streptococci resist intoxication by metals, a major...

Primary supervisor - Prof Kate KemsleySecondary supervisor - Assoc Prof Katharina Huber'Chemical space' is the vast, multidimensional landscape of all possible molecules that exist in nature or can be synthesized in the laboratory. Understanding the space is vital for natural product and drug discovery, but as yet only a tiny fraction of these so-called...

Join Norwich University of The Arts in Shaping the Future of Research SupportWith the launch of our Research and Knowledge Exchange Strategy, the University sets out a framework for the development of an ambitious and vibrant culture, which includes: the establishment of two new Institutes; research degree studentships and bursaries; East Gallery...

Accelerate Personnel are recruiting on behalf of our client Category C+E/Class 1 Drivers, within the North Norwich area.This role will vary with shift start times, from mid afternoon to evenings. This work will involve both local and national deliveries in the UK. You will be expected to provide good customer service to our clients and their end customer...

Faculty of ScienceTyndall Centre for Climate Change ResearchRef: ATR1686A competitive salary is available for an outstanding candidate. The appointment also carries an additional stipend during the Director of Tyndall Centre term.With a drive and ambition that matches the most ambitious goals of the UN Paris Agreement, the Tyndall Centre seeks an inspiring,...

UEA Professor in Climate Change Research A competitive salary is available for an outstanding candidate. The appointment also carries an additional stipend during the Director of Tyndall Centre term.With a drive and ambition that matches the most ambitious goals of the UN Paris Agreement, the Tyndall Centre seeks an inspiring, passionate and dedicated...

Applications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Wilfried Haerty in the Research Faculty of the Earlham Institute, based in Norwich, UK.Background:Climate change imposes unprecedented challenges to organisms, both through the rapid change of their environment (e.g. temperature increase, droughts) and through...

Applications are invited for a Postdoctoral Research Scientist to join the Research Faculty Department at the Earlham Institute, based in Norwich, UK.Background:In humans, over 90% of the variants associated with traits are found within noncoding regions of the genomes, either within genes' introns, untranslated regions, promoters, or within intergenic...

Salary on appointment will be £39,260 to £57,570 per annum (pro rata) on the Clinical Academic salary scale. Appointment salary level will be based on the appointee's existing salary within the NHS. The primary focus of this post will also be the Clinical Lead for the Gateway Year. This role encompasses Module Leadership of the MB BS Medicine with a...