Senior Scientist

Found in: Appcast Linkedin GBL C2 - 2 weeks ago


Cambridge, United Kingdom Nxera Pharma Full time

CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a lab-based Senior Scientist in Protein Binder Discovery based in Granta Park, Cambridge.



Company:


Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally, focused on therapeutic areas in inflammation diseases, neurology and immunology.



The Role:


The successful candidate will join the Protein Binders Discovery Team at Nxera Pharma and will also be part of the wider Biochemistry and Biophysics teams. The successful candidate will use phage display expertise to select protein binders against therapeutic membrane protein targets to enable structure determination and drug discovery efforts.


The role will include the following responsibilities:

• Screening phage display libraries against membrane protein targets

• Protein engineering of VHH frameworks

• Subcloning of plasmid constructs for expression

• Biophysical evaluation of VHH hits



Your Background:


• PhD (or MSc with equivalent lab experience) in a relevant area of biology

• Theoretical and practical expertise in phage display technologies and selection techniques

• Experience working with phage antibody libraries and preferably VHH display

• Strong and evidenced molecular biology proficiency

• Experience of screening techniques (eg ELISA, cell binding assays etc)

• Experience of affinity maturation

• Analytical thinking and good problem-solving skills




DESIRABLE:


• Experience of measuring affinity using either BLI or SPR

• Experience of library build (either affinity maturation or immunised, naïve or synthetic libraries)

• Experience in working with membrane proteins (in particular GPCRs)

• Computational expertise focussed around protein binder design would be advantageous




Apply:


It is essential that applicants hold entitlement to work in the UK. Please quote job reference 56806 in all correspondence.


  • Senior Computational Scientist

    Found in: Whatjobs ES C2 - 5 days ago


    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist. Are you a senior Computational...

  • Senior Computational Scientist

    Found in: Appcast UK C C2 - 1 week ago


    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    Found in: Appcast UK C2 - 1 week ago


    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    Found in: Appcast Linkedin GBL C2 - 1 week ago


    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...

  • Senior Computational Scientist

    Found in: Talent UK 2A C2 - 1 week ago


    Cambridge, United Kingdom SRG Full time

    I am genuinely excited to be working with a cutting edge Biotech who work at the interface of engineering and cell biology to develop human biomimetic platforms for the testing and development of therapeutics for serious human diseases. They are expanding their R&D team in Cambridge and seeking a Senior Computational Scientist.Are you a senior Computational...


  • Cambridge, United Kingdom TEC PARTNERS LIMITED Full time

    TEC Partners are working with a fast growing Life Sciences company, based in Cambridge.They are providing single cell analysis systems and specialist consumables for the global pharmaceutical and academic research community. They are growing fast and theyhave recently received a big funding round. They are looking for a Senior Microfluidics...


  • Cambridge, United Kingdom Reed Scientific Full time

    **(Senior) Scientist - Pipeline Scientist** **In this role you will be responsible for**: - Microfluidic-based NGS library preparation - Work with technology development, expression and bioinformatics teams to identify trends in sequence data and expression profiles - Trouble shooting and technology development - Establishment, review, and updates of...

  • Senior Scientist

    Found in: Appcast UK C C2 - 2 weeks ago


    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    Found in: Appcast UK C2 - 2 weeks ago


    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    Found in: Appcast Linkedin GBL C2 - 2 weeks ago


    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    Found in: Talent UK 2A C2 - 2 weeks ago


    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits.Who we areWe are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    Found in: Whatjobs ES C2 - 5 days ago


    Cambridge, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits. Who we are We are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...


  • Cambridge, United Kingdom Reed Scientific Full time

    **(Senior) Scientist - Expression Scientist** **In this role you will be responsible for**: - Development and implementation of a mammalian-based cell expression platform - Implementation of a vector platform used for the expression platform - vector design, gene synthesis and molecular biology - Significant efforts on optimisation and development of these...

  • Senior Applied Scientist

    Found in: Talent UK C2 - 1 week ago


    Cambridge, United Kingdom Evi Technologies Limited Full time

    Our team undertakes research together with multiple organizations to advance the state-of-the-art in speech technologies. We not only work on giving Alexa, the ground-breaking service that powers Echo, her voice, but we also develop cutting-edge technologies with Amazon Studios, the provider of original content for Prime Video. Do you want to be part of the...

  • Senior Scientist

    Found in: Talent UK C2 - 1 week ago


    Cambridge, United Kingdom Lonza Full time

    Here at Lonza we have a great opportunity available for a Scientist to join our Research & Development department. This is a permanent position based out of our Cambridge facility. The Scientist role involves the isolation and banking of human primary cells and the design and execution of various in vitro cell-based bioassays. The role also involves...


  • Cambridge, United Kingdom Science Solutions Recruitment Ltd Full time

    A growing Cambridge-based biotechnology company is seeking a Senior/Principal Scientist with experience in protein science and high-throughput assay development to join their team focused on the development of novel therapeutics. In this role, you will lead drug discovery projects, performing protein production, purification and protein aggregation assays,...


  • Cambridge, Cambridgeshire, United Kingdom Joynes & Hunt Full time

    Senior Research Scientist-CMC, process development Our client is a biotechnology research company. They are currently seeking a driven and organised senior research scientist to join their preclinical development team. This is an exciting opportunity for an enthusiastic candidate to work with this team to progress a leading microbiome company into clinical...

  • Senior Scientist

    Found in: Jooble UK C2 - 2 weeks ago


    Cambridge, Cambridgeshire, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits. Who we are We are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...

  • Senior Scientist

    2 weeks ago


    Cambridge, Cambridgeshire, United Kingdom Mackinnon Bruce International Full time

    Description We are working alongside our client in the Vertical Farming industry, based in Cambridge to hire a Senior Scientist, with a focus upon Soft Fruits. Who we are We are a dynamic recruitment agency that has evolved since our first establishment in 2012. We work with several high-profile clients globally to help them source and retain top-tier...


  • Cambridge, United Kingdom Wellcome Sanger Institute Full time

    Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity's greatest challenges. Would you like to help shape the future of human microbiome sciences? We have an exciting opportunity for a **Senior Staff scientist**, who is passionate...