Biotransformation Development Lead

4 weeks ago

Berkshire, United Kingdom Hyper Recruitment Solutions LTD Full time
Are you experienced in Biotransformation Development and looking for an exciting new opportunity?
We are currently looking for a Biotransformation Development Lead to join a leading biopharmaceutical company based in either Berkshire, UK or Braine, Belgium.
As the Biotransformation Development Lead, you will be responsible for contributing to development and drug discovery projects in immunology and neuroscience therapeutic areas.
KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Biotransformation Development Lead will be varied however the key duties and responsibilities are as follows:
1. Planning, performing, and interpreting metabolite profiling studies up to and including human ADME studies for regulatory submissions, including MIST evaluation.
2. Planning and coordinating outsourced metabolite profiling studies in partnership with Contract Research Organisations.
3. Providing guidance in line with regulatory requirements and applying this to biotransformation strategies.
4. Generating, reporting, and communicating metabolic profiles in different biological matrices from in vitro and/or in vivo studies, including active and reactive metabolites by interpretation of mass spectral data.
ROLE REQUIREMENTS:
To be successful in your application to this exciting role as the Biotransformation Development Lead, we are looking to identify the following on your profile and past history:
1. Relevant degree in Biotransformation, DMPK, or related areas with analytical chemistry experience.
2. Extensive industry experience in biotransformation and metabolism, particularly in supporting preclinical and clinical leads.
3. A working knowledge and practical experience in metabolite identification experience in LC/MS, bioanalytical chemistry and enzymology as well as strong knowledge of international regulatory principles and guidelines regarding human metabolites with particular emphasis on MIST.
Key Words: /Biotransformation/ /Development Lead/ /Pharmaceutical/ /Drug Discovery/ /Immunology/ /Neuroscience/ /Metabolite Profiling/ /ADME Studies/ /DMPK/ /Enzymology/
Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications for any applicant who fulfil the role requirements for this position. HRS is a company exclusively supporting the science and technology sectors, and is made up of a collaboration of recruitment professionals and scientists. We look forward to helping you with your next career moves

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