Senior Researcher – Chemistry
1 month ago
Nucleic Acid Therapy Accelerator
The Medical Research Council (MRC), as part of UK Research and Innovation (UKRI), have invested a total of £30m over 4 years through the Strategic Priorities Fund to establish a nucleic acid therapy accelerator (NATA) that will support state-of-the-art interdisciplinary research to solve critical issues in nucleic acid drug delivery, through focused NATA research challenges and a NATA infrastructure hub. This will be an internationally unique resource, drawing on world-leading academic expertise in partnership with innovative businesses to discover and test viable ways of delivering oligonucleotide therapies, anchoring the oligonucleotide therapy industry in the UK for many years to come.
The NATA will focus on bringing together key stakeholders around the infrastructure hub while catalysing collaborative R&D activity with focused support to tackle significant barriers facing oligonucleotide therapy delivery to key organs. This investment will support capacity building in terms of equipment, upskilling and domain expertise that will be essential in developing critical mass to catalyse and de-risk the development of next generation nucleic acid medicines.
The NATA has the opportunity to establish a new industrial sector attracting and developing highly skill jobs with the potential of the UK being the leader in the field where global nucleic acid therapies market is expected to be £6 billion by 2025.
The Role
The senior scientist will be critical in supporting the NATA chemistry department by being a key member of the chemistry team supporting the design, synthesis and development of new and novel therapeutic oligonucleotides for various translational and collaborative projects. The successful candidate will both work independently and be part of project teams. This individual will be involved in the design, development and testing of novel chemical modalities for Nucleic Acid delivery. This position will also include the optimization of the synthesis of Nucleic Acid Therapeutics in the direction of maximizing their potency, minimizing side effects, and employing other beneficial features that improve their therapeutic precision and impact.
Main Responsibilities
● Serve as a key member in optimizing current Nucleic Acid Therapeutic platform, development of new chemical modalities and production of multiple lead compounds.
● Play an active role in synthesis, purification and analysis of novel nucleosides, phosphoramidites and oligonucleotides with minimal supervision.
● Contribute actively to synthetic route designing, implementing new techniques and methods.
● Contribute to advanced conjugation chemistry.
● Recognise opportunities for the creation of intellectual property and cooperate in patent protection and exploitation.
● Write and submit manuscripts for publication with the Chemistry Lead R and I.
● Managing chemistry laboratory resources efficiently and troubleshooting equipment and synthetic procedures.
● Conducting quality control and preparing data sheets.
● Keeping excellent scientific records and implementing databases.
● Presenting work internally, externally and contributing to lab meetings.
● Provide regular updates on project status to the Chemistry Lead R and I.
● Participate in supervising R & D activities at external contract research organizations.
● Maintaining an up to date and deep understanding of relevant literature.
● Work effectively with collaborators.
We have other current jobs related to this field that you can find below
-
Senior Researcher – Chemistry
1 month ago
Didcot, United Kingdom Medical Research Council Full timeThe Role The senior scientist will be critical in supporting the NATA chemistry department by being a key member of the chemistry team supporting the design, synthesis and development of new and novel therapeutic oligonucleotides for various translational and collaborative projects. The successful candidate will both work independently and be part of...
-
Senior Researcher
2 weeks ago
Didcot, United Kingdom Medical Research Council Full time**Open Date** - 30/04/2024, 10:00 **Close Date** - 30/05/2024, 23:55 - Research Institute 1- NATA- Research Institute / Unit Information 1**Nucleic Acid Therapy Accelerator**: The Medical Research Council (MRC), as part of UK Research and Innovation (UKRI), have invested a total of £30m over 4 years through the Strategic Priorities Fund to establish a...
-
Didcot, Oxfordshire, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute (the Franklin) is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology.Within the Davis group in the Next Generation Chemistry theme, one of the aims is to develop new...
-
Research Chemist
4 weeks ago
Didcot, United Kingdom Reed Scientific Full timeReed Scientific is working with one of Oxfordshire’s largest chemical companies. They are looking for chemists with a passion for R&D to join their expanding research division. Interested in chemical science? Are you looking for that next step in your sciencecareer? Our client would love to hear from you! Vacancy: Research Chemist Organisation: Chemical...
-
Post-doctoral Research Associate, Bli19
3 weeks ago
Didcot, United Kingdom Diamond Light Source Full time**About Us** Diamond Light Source is the UK’s national synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry,...
-
R& D Research
1 month ago
Didcot, United Kingdom Solarverse Ltd Full timeA first degree and preferably post graduate research Commercial experience not necessary Fields of expertise in one or more of the following: Quantum Engineering, Quantum Computing, Chemistry, Mathematics, Physics, Engineering, Planetary Science, Satellite Systems, Telecommunications, Electronics, Artificial, photonics Intelligence, Robotics, Nano...
-
Didcot, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute (the Franklin) is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology. Within the Davis group in the Next Generation Chemistry theme, one of the aims is to develop new...
-
Postdoctoral Research Associate
1 week ago
Didcot, United Kingdom Diamond Light Source Full time**About Us** Diamond Light Source is the UK’s national synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry,...
-
Senior Market Research Executive
4 weeks ago
Didcot, United Kingdom The Horticultural Trades Association Full time**Senior Market Research Executive** **Permanent / Hybrid Working / Full time / Salary up to £32k DOE** We are looking for experienced market researcher to join our small market research team in the position of Senior Market Research Executive. You will be supporting the manager to conduct our association’s market and customer analysis and research,...
-
Didcot, Oxfordshire, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology. We are currently expanding and looking for a science driven, but community oriented Postdoctoral Research Associate...
-
Didcot, Oxfordshire, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute (the Franklin) is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology. Within the Next Generation Chemistry theme, one of the aims is to realise the full potential of...
-
Didcot, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute (the Franklin) is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology. Within the Next Generation Chemistry theme, one of the aims is to realise the full potential of...
-
Didcot, United Kingdom The Rosalind Franklin Institute Full timeThe Rosalind Franklin Institute is a national research centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology. We are currently expanding and looking for a science driven, but community oriented Postdoctoral Research...
-
Senior Market Research Executive
2 weeks ago
Didcot, Oxfordshire, United Kingdom The Horticultural Trades Association Full timeSenior Market Research ExecutivePermanent / Hybrid Working / Full time / Salary up to £32k DOEWe are looking for experienced market researcher to join our small market research team in the position of Senior Market Research Executive. You will be supporting the manager to conduct our association's market and customer analysis and research, helping us to...
-
Postdoctoral Research Associate
6 days ago
Didcot, United Kingdom Diamond Light Source Full time**About Us** Diamond Light Source is the UK’s national synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry,...
-
Postdoctoral Research Associate
4 weeks ago
Didcot, United Kingdom Diamond Light Source Full time**About Us** - Diamond Light Source is the UK’s national synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry,...
-
Post-Doctoral Research Associate, BLI19
1 month ago
Didcot, United Kingdom Diamond Light Source Full timeAbout the Role We now have an opportunity for a Post Doctoral Research Associate to join our team on Beamline I19 at Diamond, a facility tailored for small-molecule single-crystal diffraction. Our beamline utilizes an intense X-ray beam (5-30 keV) to delve into the intricate structural properties of various materials. You will engage in cutting-edge...
-
Post Doctoral Researcher Soft Matter
2 weeks ago
Didcot, United Kingdom Science and Technology Facilities Council (STFC) Full timePost Doctoral Researcher Soft MatterSalary: 39,375 to 48,802 per annum (dependent on skills and experience).Hours: Full timeContract Type: Fixed Term (36 months)Location: Science and Technology Facilities Council, Rutherford Appleton Laboratory Harwell, OxfordshireThe ISIS Neutron and Muon Source (ISIS), is a world-leading centre for research in the physical...
-
Beamline Scientist
1 week ago
Didcot, United Kingdom Diamond Light Source Full timeAbout the Role We now have an opportunity for a Beamline Scientist, or Senior Beamline Scientist to directly support the Principal Beamline Scientists (PBSs) on B22 and B21 during operations starting from this phase of the Diamond-II planning and early stages of development. The position will ensure smooth operations of B22 by providing beamtime to the...
-
Senior Market Research Executive
4 weeks ago
Didcot, United Kingdom The Recruitment Group Full timeThe Recruitment Group is hiring! An exciting opportunity has arisen for a motivated individual to assist with a variety of tasks as a Market Research Executive for a business based in Harwell. **Title: Market Research Executive** **Salary: £35,000 Per Annum (Full time)** **Location: Harwell, Oxfordshire - Hybrid Working** **Hours: 09:00 - 17:00 Monday...
