Senior Scientist, Evidence Synthesis

3 months ago

Newcastle Upon Tyne, United Kingdom Genesis Research Group Full time

Genesis is one of the leading evidence generation consultancies providing agile, tech-enabled real-world evidence (RWE), as well as health economics and outcomes research (HEOR) solutions to clients in the pharmaceutical, biotech, and medical device industries. Since 2009, we’ve partnered with our clients to develop impactful evidence across the product lifecycle to optimize market access for novel healthcare innovations and satisfy regulatory, provider, and payer evidence requirements. Genesis is database agnostic, regularly working across many structured and unstructured real-world data sources. As a company, we deliver services across many RWE and HEOR applications and a wide range of therapeutic areas with an emphasis on uncompromising quality, scientific rigor, and flexible solutions.


The Genesis Evidence Synthesis (ES) team works exclusively on qualitative and, in collaboration with the Genesis Biostatistics and Analytics teams, quantitative evidence synthesis activities. Our work includes systematic, structured, and targeted literature reviews, as well as meta-analysis, meta-regression, and indirect treatment comparisons (e.g. network meta-analysis [NMA], matching adjusted indirect comparisons [MAIC], etc.). The team works collaboratively with clients, their external stakeholders, and our broad team of internal experts to efficiently deliver rigorous research findings supporting varying needs in the pharmaceutical industry – competitive intelligence activities, database landscape assessments, disease and health economic modelling inputs, dossier development, internal strategy support, gap analysis, publications, HTA/payer/reimbursement submissions, regulatory submissions, and more. The Genesis team has decades of combined experience, including a strong record of peer-reviewed publications and work in evidence synthesis.




Accountabilities within this role:

  • Conducts literature searches using online tools and databases (i.e. Embase, Medline, Cochrane, preferably via Ovid) with minimal supervision.
  • Develops draft search strategies with guidance from senior team members.
  • Leverages systematic and targeted literature review methodology to identify and select relevant published literature sources with minimal supervision.
  • Performs data extraction with minimal supervision.
  • Analyzes a large evidence base and draws considered conclusions.
  • Prepares high-quality written technical reports with guidance from senior team members, in compliance with all company quality standards and processes. Such reports may include systematic or targeted literature review reporting and/or inform clinical trial packages, client internal evidence gathering, global value dossiers, or reimbursement/regulatory submissions.
  • Prepares high-quality presentations, for use within the company and externally to clients with guidance from senior team members.
  • Ensures all work is delivered with high-quality and within planned project timelines and/ or budgeted hours (if relevant).
  • Ensures proficient use of EndNote to manage referencing appropriately within reports.
  • Ensures proficient use of Microsoft Office applications to ensure clear and well formatted deliverables are delivered to clients.
  • Attends relevant internal and/ or external team meetings.
  • Contributes to the team’s development of templates, new ideas and/ or process improvements related to literature review processes within the company.
  • Contributes to the team’s development of publications and/ or posters for national or international conferences.




Qualifications:

  • 2 years industry or consulting experience in evidence synthesis work, or, more broadly in market access/ HEOR, across multiple project types and disease areas.
  • Masters or PhD within a relevant discipline.
  • Ability to work collaboratively across multiple simultaneous projects.
  • Excellent verbal and written communication skills.
  • Excellent organizational skills and attention to detail.
  • Excellent time management and ability to work within set project timelines.
  • Problem-solving skills, and the ability to find and employ creative solutions.
  • Early ability to manage projects with guidance, including setting of project goals, timelines, budget, and coordinating with the project team.
  • Early stakeholder management skills with guidance, including ability to challenge diplomatically and appropriately.
  • Knowledge of or experience with quantitative evidence synthesis (e.g. network meta-analysis [NMA], matching adjusted indirect comparisons [MAIC], etc.) preferred, but not required.
  • Technical knowledge of the market access/ HEOR environment, with specific UK/ European or US experience preferred, but not required.




Compensation:

  • Competitive salary
  • Performance-related bonus
  • Company-matched 401k plan
  • Medical/dental benefits



Genesis Research is an equal opportunity employer.

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