Clinical Research Laboratory Technician

Found in: Talent UK C2 - 2 weeks ago


Nottingham, United Kingdom Nottingham University Hospitals NHS Trusts Full time

Job summary

Our vision is to situate Nottingham University Hospitals Trust at the very forefront of clinical research placing patient needs at the centre of our research activity. Across our hospitals we have over 2000 metre squared of dedicated and purpose-built research facilities, staffed by research staff, committed to delivering cutting-edge research.

Our expertise in experimental medicine is at the forefront of COVID-19 research for effective treatments and vaccines, as well as contributing to the world's understanding of Coronavirus.

We are seeking a Clinical Research Laboratory Technician to support the delivery of our clinical research portfolio across Research & Innovation within Nottingham University Hospitals NHS Trust. The successful candidate will work closely with the Research & Innovation laboratories team to support the wider delivery team with a diverse range of research trials.

Main duties of the job

In addition to the brief list above you must familiarise yourself with the full job description and person specification attached to this advert prior to applying.

The Post Holder will be an experienced, qualified Clinical Research Laboratory Technician, and will perform work that require a degree of responsibility and autonomy, including working unsupervised for significant periods. As a Clinical Research Laboratory Technician, the post holder will be part of the Research and Innovation department including the NIHR Nottingham Clinical Research Facilities (NCRF), Nottingham Bioresource and NIHR Nottingham Biomedical Research Centre (BRC) and will work within University of Nottingham laboratories to support academic work.

The post holder will ensure the accurate handling, processing, storage and transfer of a multitude of research samples obtained through clinical trials, both commercial and non-commercial, carried out within the Research and Innovation laboratories. The post holder will be required to provide scientific and technical support to the laboratory and clinical staff within the Research and Innovation department.

The post holder may be required to work at QMC campus and/or City campus of Nottingham University Hospitals NHS Trust. They will assist in the delivery of a quality driven, cost effective, patient focused service consistent with trust objectives and values, across all R&I departments.

About us

With more than 18,000 colleagues, we are the largest employer in Nottinghamshire and one of the biggest and busiest NHS Trusts in the country, serving more than residents of Nottingham and Nottinghamshire and a further four million people across the East Midlands and beyond.

We provide a range of national and internationally renowned specialist services and we are at the forefront of new surgical procedures and research programmes. We are home to the East Midlands Major Trauma Centre, the Nottingham Children's Hospital and in partnership with the University of Nottingham we host a Biomedical Research Centre carrying out vital research into hearing, digestive diseases, respiratory, musculoskeletal disease, mental health and imaging.

This is an exciting time to join NUH and help support our future ambitions.

Job description

Job responsibilities

Under the direction of the Research and Innovation department (R&I) and the R&I Laboratory Manager, the key job responsibilities include:

Undertake routine and complex laboratory-based work such as the pre-analytical processing of clinical trial specimens and samples for analysis using various technologies.

Perform clerical tasks including, monitoring and querying sample processing requests made by the clinical team, completing sample tracking logs, equipment maintenance logs, and other documentations appropriate for the role.

Accurately follow, or in some cases design, protocols to ensure the smooth running of the facility and the accurate processing of study samples.

Collect, catalogue and store human tissue, blood and urine samples from within the R&I department, Nottingham University Hospitals or external sites. Manage sample storage facilities and maintain collections - this will involve out of hours monitoring of sample freezers.

Organise sample retrieval from external sites. From time to time, some of this work may be out of hours therefore some flexibility within working hours is essential.

Culture of epithelial and smooth muscle cells from human lung biopsies.

Process human sputum samples including differential cell count.

To accurately record sample transfers both in and out of University of Nottingham and R&I laboratories

Isolate stored samples for transfer to or from the University of Nottingham and R&I laboratories, this will involve arranging couriers and ensuring samples are packed appropriately.

Observe all GLP, GCP, HSE and HTA regulations. Maintain records to comply with Human Tissue Act, including assisting with sample audits. To adhere to Trust policy and procedures and University Health and safety.

Be responsible for the upkeep of the lab areas and equipment. Maintain laboratory stock levels of chemicals and consumables and ensure adequate equipment maintenance.

Maintain and clean laboratory equipment and maintain a high standard of housekeeping within the laboratory.

Any other duties appropriate to the role and level.

To assist in the induction, and training of new laboratory staff, providing mentorship and support within the clinical team.

To contribute to the development of clinical and research policies, and Standard Operating procedures.

To act as a resource for colleagues in relation to clinical studies.

To attend relevant training and to gain experience from other laboratories. This may mean some travel is involved.

To keep appropriate staff informed of the progress of clinical studies.

To maintain an up-to-date knowledge of relevant research related articles particularly related to clinical studies.

To continue your own professional development according to appropriate regulatory guidance, keeping updated with current practice.

To assist with training of placement students in relevant scientific techniques

To attend national meetings/conferences in relation to clinical studies as appropriate and agreed with R&I Laboratory Manager

Person Specification

Training and Qualifications

Essential

BSc in a biological or biomedical subject Attained or working towards NVQ level 3 in Clinical Laboratory Support orequivalent qualification or equivalent experience Extensive experience as a scientist/technician working in an academic or healthcare/clinical laboratory Knowledge and experience of Good Laboratory practice and research governance Demonstrates a commitment to continuing education and training Can maintain confidentiality and act professionally

Desirable

MSc in a biological or biomedical subject Demonstrates a knowledge and awareness of instrumentation, method development and new technologies

Experience

Essential

Excellent, demonstrable experience and technical competency in processing human tissue samples. Knowledge of Equal Opportunities, Human Tissue Act & Data Protection /Confidentiality. Knowledge of GCLP and Health & Safety legislations related to the Laboratory. Conscientious and Meticulous, demonstrates ability to organise their own work effectively Keyboard skills and computer literacy.

Desirable

Demonstrable experience and technical competence in complex ( PBMCs, Sputum, and Cell Culture) sample processing and laboratory procedures. Experience of laboratory management and quality control. Experience of laboratory stock control. Training junior staff.

Communication and Relationship Skills

Essential

Good interpersonal skills. Able to communicate concisely, effectively and clearly Able to work well in a team and as an individual Can maintain confidentiality

Desirable

Demonstrates a range of IT skills

Planning and Organisation Skills

Essential

Able to plan own work activities and those of supervised staff Able to meet agreed targets on an ongoing basis

Analytical and Judgement Skills

Essential

Able to make judgements regarding complex facts or situations that require analysis, interpretation and comparison of a range of options. troubleshooting & resolving issues such as mismatched samples, QA assessments and technical failures

Desirable

Experience of troubleshooting in a laboratory setting.

Physical Skills

Essential

Manual dexterity required to perform tasks Physically capable of carrying out laboratory tasks and capable of intense periods of concentration

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