DMPK Project Lead

2 weeks ago

Slough, United Kingdom Lifelancer Full time

The individual will have projectresponsibility for early discovery towards candidate selection andinto the clinical phases of the development. They will beresponsible for the project aspects of nonclinical DMPK includingin vitro and in vivo activities preclinical PK translational PK andPKPD biotransformation and bioanalysis contributions to projects tofulfil internal and regulatory requirements up to and includingregistration.

What youlldo

  • Designappropriate experimental studies and liaise with other areas of theRD organization to deliver data and interpretations to support theproject towards candidate selection andbeyond
  • Have expert understanding of thedifferent approaches related to preclinical pharmacokinetics aswell as a good understanding of related disciplines (e.g.toxicokinetics nonclinical safety PKPD PK modelling drug designclinical DMPK bioanalytics andbiomarkers)
  • Apply their understanding ofphysical properties DMPK and enzymology to input into the design ofnew compounds
  • Work with the project andDevelopment Sciences colleagues to resolve or riskmitigateprojectrelated ADME challenges
  • Work with otherareas in the DMPK organization to champion new innovativeapproaches to project support and ensure UCB stays at the forefrontof DMPK science
  • Prepare the DMPK sections ofinternal and regulatory documents (e.g. IND IMPD IBNDA)
  • Participate in research aligned to DMPKand UCBs portfolio to publish research papers in internationallyrecognized journals
  • Provide scientificmentorship to support junior staff in their personaldevelopment



Interested For this rolewere looking for the following education experience andskills

  • PhD(or equivalent) in Pharmaceutics Pharmacology Drug metabolism orPharmacokinetics with 7 years of PostDoctoral Industrialexperience; or a related degree with 10 years industrial experiencein DMPK science.
  • A comprehensive understandingof discovery and development DMPK including modelling andsimulation and a proven ability to delineate the impact of chemicalstructure on measured properties
  • Wideexperience in pharmaceutical RD including a knowledge of theregulatory requirements and experience working with regulatoryagencies to fulfil the DMPK contribution to new drugsubmissions
  • A recognized track record ofexperience in DMPK/ADME and excellent knowledge inADME/Enzymology/Drug Transporters and knowledge of how to coupledata to optimization/selection of NCE both in discovery anddevelopment
  • A proven track record of leadingunderstanding and handson experience of drug metabolism andpharmacokinetics both in vitro and in vivo studies human PKprediction DDI prediction and mechanistic understanding to supportlatestage programs
  • Understanding of PKPD andpreferably an understanding of PBPKmodeling
  • Proven skills for in depth mechanisticunderstanding of DMPK related issues and of the impact and value oftranslation to humans
  • Knowledge of the drugdevelopment processes in the Pharma Industryenvironment.

Lifelancer( ) is a talenthiring platform in Life Sciences Pharmaand IT. The platform connects talent with opportunities in pharmabiotech health sciences healthtech data science and ITdomains.

Please use the below Lifelancer linkfor job application and quickerresponse.

/jobs/view/7d2133ddbdb4e602110f7018db411493

RemoteWork :

No

  • DMPK Project Lead

    10 hours ago

    Slough, United Kingdom Lifelancer Full time

    The individual will have project responsibility for early discovery towards candidate selection and into the clinical phases of the development. They will be responsible for the project aspects of nonclinical DMPK including in vitro and in vivo activities preclinical PK translational PK and PKPD biotransformation and bioanalysis contributions to projects to...

  • Dmpk Project Lead

    3 months ago

    Slough, United Kingdom UCB S.A. Full time

    **Make your mark for patients** We are looking for a **DMPK Project Representative** who is curious and innovative to join us in our Quantitative Discovery & Development team, based at our research site in **Slough, UK** or **Braine L’Alleud, Belgium**. **About the role** The DMPK project representative is a critical role in our R&D activities, and we...

  • DMPK Project Lead

    3 weeks ago

    Slough, Slough, United Kingdom UCB Full time

    Make your mark for patients We are looking for a DMPK Project Representative who is curious and innovative to join us in our Quantitative Discovery & Development team, based at our research site in Slough, UK or Braine L'Alleud, Belgium. About the role The DMPK project representative is a critical role in our R&D activities, and we are looking to recruit a...

  • DMPK Project Lead

    3 months ago

    Slough, United Kingdom UCB Full time

     Make your mark for patients  We are looking for a DMPK Project Representative who is curious and innovative to join us in our Quantitative Discovery & Development team, based at our research site in Slough, UK or Braine L’Alleud, Belgium. About the role The DMPK project representative is a critical role in our R&D activities,...

  • Senior DMPK Project Lead

    2 weeks ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled Senior DMPK Project Lead to join our team at Lifelancer. As a key member of our organization, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Oversee projects from early...

  • DMPK Project Lead

    3 hours ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    36 minutes ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    4 hours ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    3 hours ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    2 hours ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    3 minutes ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to early discovery, candidate selection, and clinical phases of drug development.Key ResponsibilitiesProject Leadership: Design and execute...

  • DMPK Project Lead

    3 hours ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to drug metabolism and pharmacokinetics (DMPK) and absorption, distribution, metabolism, and excretion (ADME).Key ResponsibilitiesProject...

  • DMPK Project Lead

    32 minutes ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly experienced and skilled DMPK Project Lead to join our team at Lifelancer. As a key member of our research and development team, you will be responsible for leading projects related to drug metabolism and pharmacokinetics (DMPK) and absorption, distribution, metabolism, and excretion (ADME).Key ResponsibilitiesProject...

  • DMPK Project Lead

    2 weeks ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleThe successful candidate will be responsible for leading projects in early discovery and development, focusing on candidate selection and clinical phases. This role will oversee nonclinical DMPK activities, including in vitro and in vivo studies, pre-clinical PK, translational PK and PK-PD, biotransformation, and bioanalysis. The individual...

  • Chemical Project Director

    4 days ago

    Slough, Slough, United Kingdom Lifelancer Ltd Full time

    About the RoleWe are seeking a highly experienced and skilled Chemical Project Director to join our team at Lifelancer Ltd. As a key member of our research and development department, you will be responsible for leading projects from early discovery to clinical phases, ensuring the successful development of new compounds.Key ResponsibilitiesProject...

  • Chemical Project Director

    5 days ago

    Slough, Slough, United Kingdom Lifelancer Ltd Full time

    About the RoleWe are seeking a highly experienced and skilled Chemical Project Director to join our team at Lifelancer Ltd. As a key member of our research and development department, you will be responsible for leading projects from early discovery to clinical phases, ensuring the successful development of new compounds.Key ResponsibilitiesProject...

  • Biotransformation Development Lead

    4 days ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly skilled Biotransformation Development Lead to join our global team and contribute to the development and drug discovery projects in immunology and neuroscience therapeutic areas.Key ResponsibilitiesPlan, perform, and interpret metabolite profiling studies, including human ADME studies for regulatory submissions, in...

  • Biotransformation Development Lead

    2 weeks ago

    Slough, Slough, United Kingdom Lifelancer Full time

    About the RoleWe are seeking a highly skilled Biotransformation Development Lead to join our global team and contribute to the development and drug discovery projects in immunology and neuroscience therapeutic areas.Key ResponsibilitiesPlan, perform, and interpret metabolite profiling studies, including human ADME studies for regulatory submissions, in...

  • Biotransformation Development Lead

    4 weeks ago

    Slough, Slough, United Kingdom UCB Full time

    Make your mark for patientsWe are looking for a talented individual to fill the position of Biotransformation Development Lead to strengthen our global Biotransformation and Enzymology team by contributing to development and drug discovery projects in immunology and neuroscience therapeutic areas. The role can be based in either Braine, Belgium or Slough,...

  • Biotransformation Development Lead

    1 month ago

    Slough, United Kingdom UCB Full time

     Make your mark for patientsWe are looking for a talented individual to fill the position of Biotransformation Development Lead to strengthen our global Biotransformation and Enzymology team by contributing to development and drug discovery projects in immunology and neuroscience therapeutic areas. The role can be based in either Braine, Belgium or...