Oligonucleotide Production Scientist
2 weeks ago
Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC and Europe.
Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.
Oxford Nanopore’s sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths. Our goal is to enable the analysis of any living thing, by anyone, anywhere
We are looking for a highly motivated individual to join the Oligonucleotide Production team as a Production Scientist supporting the purification and manufacturing of highly complex oligonucleotides.
The Details...
This is an exciting and challenging role as part of the newly established Oligonucleotide Production facility based at the Harwell Campus site. The oligonucleotide production team aims to produce a range of high-quality, complex oligonucleotide standards to support our Sequencing Kit product range. Collaboration, innovation, and quality are at the forefront of our team’s vision as we grow the facility to support the rapid expansion of the product range.
The successful candidate will work closely with other members of the team to establish and run the manufacturing processes for the oligonucleotide purification facility. This is an opportunity to help shape a new department providing real impact to the wider company. As a valued member of the team, you will have the opportunity to develop your career in this dynamic environment.
A day in this role might include: Purification of complex oligonucleotides primarily using preparative HPLC. Performing HPLC, CE and LC-MS analytical testing for in-process and end-point monitoring of quality. Carrying out oligonucleotide conjugation procedures and SPE clean-up protocols. High throughput, automated sample handling workflows ensuring low cross-contamination. Following quality systems in line with ISO standards. Upkeep of laboratory space including the maintenance of analytical instrumentation. Ensuring a safe working environment for all team members and a culture of continuous improvement for health & safety. Ensuring the smooth transfer of new purification methods from Development into Production. Preparing clearly articulated experimental reports and maintaining well-organised records. Working and communicating effectively with other groups in Manufacturing, Supply Chain, Procurement, Development and external suppliers. Time to focus on career development and building connections within the company.What We're Looking For...
A clear and consistent focus on the highest safety standards. Experience in a relevant industrial production environment. Experience working in a GxP regulatory laboratory would be advantageous. BSc, MSc or PhD in a relevant subject would be advantageous. Good working knowledge of oligonucleotide analytical and preparative techniques is desired. Strong problem solving and analytical skills. Excellent collaborative, interpersonal and communication skills. Organisation skills and attention to detail will be essential.Training will be given and, as such, a willingness to learn and develop is required.
Applications are encouraged from highly motivated individuals who enjoy taking on new challenges, are quickly adaptable in an exciting and fast-paced environment, and who perform well under pressure.
We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.
If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today
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