Research Associate in Microfluidic Nanocarrier Production
Found in: Talent UK C2 - 1 week ago
This exciting position, funded by Cancer Research and Prostate Cancer UK, combines microfluidic device engineering, membrane protein reconstitution and drug delivery towards the rapid production of next-generation biomimetic nanomedicines designed to sense the prostate cancer microenvironment. This position will form part of a two-PDRA project team focused on testing the translational potential of such nanomedicines to deliver compounds capable of remodelling prostate cancer tumours for the first time.
The position is aimed at outstanding scientists interested in developing skills in microfluidic device design and production, membrane protein reconstitution, on-chip biomimetic nanocarriers synthesis and their application to cancer biology and medicine. In this role you will be developing new approaches towards the integration of membrane proteins into lipid nanocarriers produced via microfluidics, building on recent advances in vesicle-based tumour sensing by the Membrane Biophysics Group. You will work across a highly multidisciplinary team composed of two research groups (Membrane Biophysics Group (Ces, Hindley) and Androgen Signalling and Prostate Cancer (Bevan)) plus collaborators in Cancer Imaging (Aboagye) and Nanotechnology (Kamaly) aiming to apply innovation in nanomedicine production to develop novel tumour-responsive delivery formulations. This outstanding multidisciplinary research environment also offers a broad range of staff support and career development opportunities.
To view the other Research Associate position that forms the second half of this project, please follow this link (job reference MED04527):
In addition to direct research duties, you will undertake project management, take responsibility for day-to-day supervision of students working on associated projects, submit publications to refereed journals and contribute to attracting external research funding.
Design and produce microfluidic and millifluidic devicesUse micro and millifluidic devices to produce lipid nanocarriers containing membrane protein componentsCharacterise nanocarriers using techniques including dynamic light scattering and cryo electron microscopyTo take initiatives in the planning of researchTo direct the work of small research teams.Hold, or be near completion of, a PhD in microfluidics, membrane biophysics, nanomedicine or synthetic cell engineering, or equivalent research or industrial experienceSignificant practical experience in microfluidic technology development.Practical experience within a research environment and / or publication in relevant and refereed journalsPractical experience within a research environmentPractical experience in a range of research techniques (see job description for details)Track record in developing scientific work for publicationExperience in communicating work to diverse audiencesWillingness to work flexibly, undertake necessary training and work as part of a dynamic team.
This is a full time, fixed term position initially for 26 months with the possibility of extension.
You will be based at White City Campus and collaborate closely with the Androgen Signalling and Prostate Laboratory led by Professor Charlotte Bevan at the nearby Hammersmith Hospital Campus.
Please note the maximum salary on appointment is £47,376 per annum.
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant.
The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. /
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