Clinical Research Fellow in Advanced Radiotherapy
2 weeks ago
Job summary
A 1- year fellowship has been created to allow the successful candidate to gain specialist training in advanced radiotherapy. The particular emphasis of this fellowship will be towards the technological advances in Radiation Oncology. The fellowship will allow the candidate to gain in depth experience in advanced radiotherapy techniques such as IMRT (intensity-modulated radiotherapy) and advanced image-guided radiotherapy using the MR-Linac. There will also be the opportunity to gain research experience and pursue original research is an opportunity for the candidate to launch a career in world-leading cancer research. They will play a part in improving treatment-decision making for patients with locally advanced Non-Small Cell Lung cancer (NSCLC) by identifying biomarkers that can be used to stratify patients in future clinical trials. A range of high- quality data has already been collected in the VIGILANCE study including ctDNA patterns, radiomics features from imaging and electronic patient reported outcome measures (ePROMs). Their role will be part of our overall strategy to make more use of routinely collected data to personalise treatment approaches and improve patient outcomes for are looking for candidates with ambition, commitment, a passion to improve patient outcomes and a strong desire to develop a career in cancer research.
Main duties of the job
This position is suitable for individuals who wish to gain specialist training in advanced radiotherapy research. The post holder is required to have obtained a FRCR qualification or equivalent prior to commencing this post. This post is for 40 hours per week to provide support for the appropriate clinics and research that is taking place in the department of Radiotherapy Related Research post holder will also play an active role in the recruitment of patients onto lung cancer clinical trials and in all aspects of care for patients enrolled on these trials. They will work closely with other members of the multidisciplinary teams and will support the consultants, clinical fellows, specialist registrars, and clinical research nurses in managing the clinical trial portfolio of the Lung Cancer Research Team.
It is anticipated the post-holder will attend appropriate clinics per week (a maximum of one research and one NHS clinics), and multidisciplinary meetings. In addition, they will participate in clinical research meetings and any other relevant trial planning or trial set-up meetings. The post-holder will also spend time analysing clinical data, writing abstracts/manuscripts, planning new studies and attending educational meetings.
About us
The Lung team comprises 9 Consultants, 2 Sub-specialty Trainee and 2 Clinical Fellows. We are supported by a team of 4 Clinical Nurse Specialists. We are friendly, hard-working team focused on delivering high quality patient-centred care. We encourage all members of team to engage in SMDT, clinics and inpatient have a team of 8 research radiographers led by a team leader who implement radiotherapy (RT) clinical trials including access to advanced technologies such as MR-Linac and average, the team can be managing 20 recruiting studies and 20 studies in follow-up with Principal Investigators across clinical oncology and have access to a National Institute for Health Research Clinical Research Facility on-site. This facility gives us access to a dedicated unit to treat patients on trials and a research laboratory to process clinicalThe Radiotherapy Related Research department has world-leading collaborative researchers in RT immunology, radiobiology, biomarkers, pre-clinical drug RT combination studies, RT physics, computational oncology and Proton Beam Therapy. Its ambition is to drive Phase I-III clinical trials with state-of-the art radiotherapy, alongside imaging and biological prognostic and predictive biomarker development including genomics, transcriptomics and proteomics.
Job description
Job responsibilities
Duties
1. Recruit patients for the VIGILANCE study, analyse the data and present the findings. This role also involved conducting translational research in collaboration with CRUK National Biomarker Work with other clinical oncologists, physicians, radiotherapy planning specialists, physicists, methodologists, and statisticians to ensure a collaborative working3. Be involved in the clinical management of lung cancer patients receiving radiotherapy Interact with allied research Supervise entry and treatment of patients in clinical studies6. Support the Lung Cancer Research Team in the delivery of clinical Undertake projects related to radiotherapy-related research including patient recruitment, data analysis, protocol and grant Produce, or contribute towards, high impact peer-reviewed Disseminate research findings through presentations at seminars and conferences.
Line Management
The post holder will be responsible to Professor Corinne Faivre-Finn, Professor of Thoracic Radiation Oncology, University of Manchester/Honorary Consultant in Clinical Oncology, The Christie NHS Foundation Hospital
Person Specification
Qualifications
Essential
Postgraduate qualifications in medicine, such as the MRCP or equivalent FRCR or equivalent GMC registration
Training
Essential
General oncology training
Desirable
Track record of significant contribution towards peer-reviewed journal articles Track record of collaborating in multi-disciplinary environments
Experience
Essential
Experience in oncology and lung cancer Experience in clinical trials and translational research Experience of working in an academic environment Ability to work with the multidisciplinary team Overview of governance, ethics and other regulatory issues ( data transfer agreements) Knowledge in the management of patients with cancer Knowledge of cancer research Developments in oncology practice
Desirable
Experience of technical radiotherapy, functional imaging and 4D CT radiotherapy lung cancer planning Experience of biomarker research such as Image Based Data Mining and/or analysis of circulating biomarkers Experience of working with Patient Reported Outcome Measures both clinically and as a research tool Experience with clinical databases-
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