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Senior Research Scientist

1 month ago

London London London London, UK, United Kingdom Barrington James Full time

We’re recruiting for a clinical-stage biotech, that pioneers transformative technologies that allow precise control of gene expression. Utilising AAV vector technology, our client has a rapidly growing portfolio covering a variety of therapeutic areas such as neurodegeneration, oncology, metabolic diseases and degenerative ocular diseases.

The Role

The role of Senior Research Scientist is to provide technical execution of development projects and support the preclinical group in vector development. You will utilise your skills and knowledge in AAV vector development to enhance the drug pipeline within preclinical development.

  • Utilise understanding of AAV vectorology and molecular biology to help advance the AAV platform Assist in developing our next-generation AAV platform and constructing and screening of libraries of capsid variants Design and execute assays for quantitative assessment of gene expression in cell models and assist in AAV vector production

Candidate profile

The successful candidate for the role of Senior Research Scientist will have the following skills and experience:

  • Deep theoretical knowledge in molecular biology, general vector design and AAV vectorology
  • Strong technical skills in molecular biology with a primary focus on cloning techniques
  • Knowledge and experience with AAV biology and production
  • Experience with analytical techniques such as Western Blot, qPCR, flow cytometry, with the ability to perform robust data analysis and interpretation, troubleshooting and optimisation
  • Knowledge of CNS/Neuroscience-based research, especially retina and/or brain
  • Have a PhD degree in molecular/biological sciences; or MSc degree in molecular/biological sciences and 1-3 years of academic/ biotech industry experience; or BSc degree in molecular/biological sciences and 3-5 years of academic/ biotech industry experience