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Associate Director, Biopharmaceutics

3 weeks ago

Oxford, United Kingdom Exscientia Full time

**About Us**

Exscientia is an AI-driven pharmatech company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting.

**The Role**

As Associate Director Biopharmaceutics, you will provide fundamental understanding of in vivo drug product performance and define adequate biopharmaceutics strategies at all stages of development in alignment with the global business strategy. You will be responsible for leading a comprehensive and strategic approach to developing and executing integrated global CMC strategies to fully integrate the deliverables of the CMC development plan within the objectives of the discovery and drug development teams. You will also represent the company with domestic and international regulatory authorities, contractors and corporate partners as needed.

Please note this is a remote/ hybrid role and occasional travel is required to our office in Oxford, UK (approximately once a quarter), with flexibility to work from home in the UK the remaining time. We are a flexible working organisation and we’re willing to consider other options which would provide similar contact time with the team.

**You will have the opportunity to**:

- Manage and lead all Biopharmaceutics deliverables and formulation strategy aspects of late-stage lead optimisation, preclinical and clinical projects at Exscientia, to agreed timelines and budget by interacting with internal and external multidisciplinary teams in a virtual development organisation.
- Act as the internal expert when discussing Biopharmaceutics and formulation strategy with our Pharma partners.

**Requirements**:
**Essential skills**:

- PhD with a minimum of ten years in the pharmaceutical industry and 7-9 years of experience in the field of biopharmaceutics, drug absorption/ pharmacokinetics, PBPK modelling, in-silico platforms and/or drug delivery of small molecules.
- Experienced in managing projects with external CROs and CDMOs/CMOs including all aspects of external vendor selection and management (with demonstrable success working with internal and external partners to meet deliverables).
- Experienced in IND, CTA and preparations for regulatory authority interactions; thorough knowledge of relevant FDA and EMEA regulations.

**Desirable skills**:

- Expertise and experience in formulation design and development is an advantage.

**Benefits**
- Work together to make a positive contribution to patients by revolutionising the pharmaceutical industry through AI-driven discovery
- Opportunity to join an inclusive, collaborative and intellectually stimulating culture
- We will work with you to provide a highly competitive compensation as we continue to grow and thrive
- Our team’s health and well-being is important to us we offer a generous holiday allowance, provide flexible working and remote working to encourage all of our team to manage their own work, time and life along with wellbeing and mindfulness support
- When you are in the office, you will have access to a kitchen stocked with an endless supply of food for all employees. Along with access plenty of break out areas so you can get to know the people you are working with. Some of the best ideas start with a coffee break
- Hear from our team why they enjoy working here.