Scientific Officer

4 days ago


London, United Kingdom The Institute of Cancer Research Full time

**Key Information**:
**Duration of Contract**: Fixed Term for 12 months

**Hours per week**: 35 hours per week (Full Time)

**Closing Date**: 13th September 2024

**Job Details**:
Under the leadership of Dr Sally George we are seeking a highly motivated Scientific Officer to work in the Developmental Oncology Group based in Sutton. The position will provide scientific support for the laboratory. Responsibilities will include maintaining an efficient and safe laboratory and organising laboratory supplies. Lab based work will include _in-vitro_ cell culture work with the opportunity to perform experiments using these models (e.g. western blotting, PCR, immunofluorescence) to address specific hypotheses. This post will complement our team of three post-doctoral fellows and one PhD student who are focused on obtaining a better understanding of the biology of difficult to treat tumours of childhood in order to identify specific therapeutic vulnerabilities.

**Key Requirements**

**Department/Directorate Information**

Dr Sally George is a team leader, within the division of Clinical Studies and the Centre for Paediatric Oncology Experimental Medicine (POEM). She is an academic clinician with a track record in translational research, including the identification of specific therapeutic vulnerabilities in neuroblastoma (_George et al, EBioMedicine 2020, George et al, JECCR 2020_) and the development of clinical biomarker initiatives for children with cancer (_George et al EJC, 2019, Bellini et al JCO, 2021, Stankunaite et al 2022_). She is also the Chief Investigator of ‘MIBG-PARP’ a transatlantic phase I/II clinical trial for children with relapsed/refractory neuroblastoma. During a secondment to the Francis Crick Institute, she developed expertise in human stem cell models and identified mechanisms of differentiation block relevant to understanding both to the drivers of oncogenesis and therapeutic resistance in neuroblastoma.

Building on this experience she established The Developmental Oncology Team at ICR in 2023, focusing on building a greater insight into the developmental biology of childhood cancers to drive therapeutic discoveries.

**About The Institute of Cancer Research**:
**Why work for us?**

As a member of staff, you'll have exclusive access to a range of staff benefits.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here_._



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