Research Fellow in Kshv-host Cell Interactions
2 weeks ago
**Research Fellow in KSHV-Host Cell Interactions**:
**Are you an early career researcher looking for your first challenge? Do you have a background in Molecular virology and virus-host cell interactions Do you want to further your career in one of the UK’s leading research intensive Universities?**
**Project Title: Kaposi’s sarcoma-associated herpesvirus manipulation of nuclear sub-domains**
The Whitehouse research group is seeking a highly motivated Research Fellow to investigate how the human tumour virus, Kaposi’s sarcoma-associated herpesvirus (KSHV), manipulates ribosome biogenesis pathways and nuclear condensates to enhance its own replication. The project will use a range of molecular and cell biology approaches to highlight a novel KSHV-mediated mechanism to regulate viral gene expression. Moreover, this project aims to identify a novel targets for antiviral intervention for this important human tumour virus.
For this role, you should have a PhD (or close to completion) in molecular virology or a closely allied discipline. You should also have experience in growth, analysis and manipulation of Kaposi’s sarcoma-associated herpesvirus, as well as in virus-mediated manipulation of ribosome biogenesis pathways and nuclear condensates.
Experience in a wide range of RNA-based techniques, qRT-PCR, protein production, mammalian cell culture, immunoblotting, and lentivirus-shRNA depletion approaches in B cells is also essential.
**To explore the post further or for any queries you may have, please contact**:
Professor Ade Whitehouse, Professor of Molecular Virology
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