Principal Investigator

6 days ago

London, Greater London, United Kingdom Barrington James Full time £60,000 - £120,000 per year

Job Description

Principal Investigator – East London

A well-established and fully integrated clinical research organization is seeking a Principal Investigator (PI) to join its team in East London. This organization is committed to advancing innovative medical treatments through excellence in patient care and the generation of high-quality clinical data.

The company supports its employees with competitive benefits, professional development opportunities, and a strong emphasis on teamwork, integrity, and patient-centered care. Benefits include medical, dental, and vision insurance, paid time off and holidays, a 401(k) retirement plan with company match, and an annual incentive program.


Position Summary

The Principal Investigator is responsible for the medical oversight, execution, and management of clinical trials conducted at the site. This role requires strong collaboration with internal teams and external sponsors, while ensuring adherence to regulatory requirements and ethical standards in research.


Key Responsibilities

  • Provide overall medical direction and oversight for clinical trials
  • Review and approve study protocols and ensure alignment with good clinical practice (GCP)
  • Protect the safety, rights, and confidentiality of all study participants
  • Evaluate medical history, perform physical examinations, and conduct study-related assessments
  • Interpret clinical data, lab results, ECGs, and diagnostic reports
  • Report Serious Adverse Events (SAEs) in compliance with regulatory timelines
  • Oversee administration of investigational products and adherence to study protocols
  • Maintain thorough and timely documentation of all study-related activities
  • Ensure compliance with IRB/ethics committee requirements and regulatory guidelines
  • Support study feasibility assessments and provide medical expertise for sponsor inquiries
  • Participate in monitoring visits, audits, and inspections
  • Ensure appropriate follow-up and care for participants if a trial is suspended or terminated
  • Maintain essential study documents and support archival and regulatory obligations
  • Perform other study-related duties as assigned

Required Skills & Competencies

  • In-depth understanding of ICH GCP, FDA regulations, and clinical research ethics
  • Strong clinical judgment and attention to detail
  • Effective and flexible communication skills
  • Analytical thinking and dynamic problem-solving abilities
  • Ability to collaborate with cross-functional teams
  • Willingness to travel up to 10% for meetings and conferences

Qualifications

  • M.D. or D.O. with a valid and active medical license (must be valid in the state where the research is conducted)
  • Board certified or board eligible in a relevant specialty
  • Certification in Good Clinical Practice (GCP)
  • Prior experience in clinical trials or research (preferred)
  • Willingness to complete company-required training and adhere to standard operating procedures (SOPs)

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