Scientist /Senior Scientist – Biophysics

The High Throughput Characterisation (HTC) team in Large Molecule Research (LMR) is seeking a Scientist in Biophysics based in Stevenage UK. This role is a fixed term contract ending December 2026.

Large Molecule Research (LMR) is a department involved in the discovery of novel and effective medicines. This department comprises several complementary functions focused on the progression of a portfolio of molecules from initial discovery, expression and characterisation, to molecular engineering and biological and physicochemical profiling, and mechanistic understanding.

This lab-based role employs state-of-the-art SPR and label-free binding technologies—as well as SEC, HIC, and DSF—to thoroughly characterize the biophysical properties of therapeutic molecules throughout the antibody discovery process. You will collaborate with multidisciplinary teams, generating data critical to drug discovery, and should possess strong communication skills as well as experience in analysing extensive datasets and working with (multi-specific) antibodies. This opportunity is ideal for a recent PhD graduate or a scientist with laboratory experience eager to advance their career and drive innovation in GSK's mission to get ahead of disease.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

In this role you will:

• Plan and execute experiments to characterize protein-protein interactions using techniques such as SPR, BLI, and other label-free binding methods.
• Assess biophysical properties of therapeutic molecules using techniques like SEC, HIC, and DSF.
• Analyse and interpret experimental data to support therapeutic discovery campaigns.
• Collaborate with multidisciplinary teams to present findings and contribute to program progression.
• Maintain accurate records of experiments and prepare scientific reports.
• Stay updated on advancements in biophysical techniques and apply them to improve workflows.

Why you?

Basic Qualifications & Skills:

We are looking for a professional with these required skills to achieve our goals:

• PhD or equivalent in biophysics, biochemistry, protein analytics, or a related discipline.
• Experience with biophysical techniques such as SPR, BLI, SEC-HPLC, HIC-HPLC, or DSF.
• Strong analytical and data interpretation skills.
• Ability to multitask and prioritize effectively while maintaining attention to detail.
• Adaptability to learn new techniques and scientific areas quickly.
• Excellent communication and collaboration skills to work effectively in multidisciplinary teams.
• Strong team-working skills and a proactive approach to collaboration .

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Experience analyzing and interpreting large and complex datasets.
• Expertise in characterizing antibodies and multispecific antibodies using HPLC-based techniques.
• Demonstrated problem-solving abilities in experimental workflows.
• Interest in data science and its application to biophysical research.
• Experience with SPR for protein-protein interaction analysis.

Join us in this impactful role where your expertise will contribute to the discovery of innovative medicines that improve lives.

Closing Date for Applications: 30th October 2025

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.

Find out more:

Our approach to R&D

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

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