Principal Scientist PKPD

11 hours ago


Slough, United Kingdom CK GROUP Full time £150 - £200

OverviewCK Group are recruiting for a Principal Scientist PKPD to join a global pharmaceutical company on a contract basis initially for 12 months.Skills, Experience, Qualifications, If you have the right match for this opportunity, then make sure to apply today.Salary: £35.20 Per hour (PAYE) / £47.92 (Umbrella) - flexible for experienced candidates.RoleParticipate in the development of non-clinical PKPD and GLP toxicokinetics studies. Lead the non-clinical PKPD strategy. Participate in protocol designs and writing by providing scientific support and input into regulatory study designs and protocols.Work collaboratively with project team representatives (e.g. Non-Clinical Safety, Bioanalysis, Clinical Pharmacology) and with CROs to ensure high quality data is generated.Deliver PKPD study reports and integrated summaries of the studies and participate in regulatory submission documents.Facilitate the advancement of drug candidates by building a thorough knowledge of the drug pharmacology and PKPD.Work collaboratively with project team representatives (e.g. Non-Clinical Safety, Bioanalysis, Clinical Pharmacology) and with CROs to ensure high quality data is generated.Your BackgroundExperience working in a matrix environment, to help design and set non-clinical PKPD study protocols, and analyze, interpret, and report PKPD results including GLP toxicokinetics studies.PhD/MSc/BSc in a relevant discipline (quantitative pharmacology; pharmacokinetics/pharmacodynamics; DMPK, etc.) with more than 5 years hands-on experience in PKPD data analysis within a pharma company or CRO environment.Good understanding of pharmacology and pharmacologic processes related to disease and drug mechanisms.Hands-on experience in delivering high quality pre-clinical PKPD data analysis. Proficiency in the use of Phoenix-WinNonlin for PKPD analysis is essential. Use of other modelling and simulation packages and tools, such as Berkeley Madonna and/or R would be advantageous.Good written and verbal communication skills, and ability to communicate study results and produce high standard reports that meet regulatory submission standards. Record of publications and other external scientific contributions relevant to PKPD will be a plus.CompanyOur client is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.LocationThis role is based at our client’s site in Slough. xpwpeyx ApplyFor more information, or to apply for this Principal Scientist PKPD, please contact the Key Accounts Team on or email Please quote reference 151 364. It is essential that applicants hold entitlement to work in the UK.Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.



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