Senior Scientist, Process Modelling

Job Title: Senior Scientist, Process Modelling Location: Macclesfield Salary: Competitive Introduction to role Are you ready to make a difference in the world of pharmaceutical development through advanced modelling and simulation? At AstraZeneca, we are committed to transforming patient lives globally with life‑changing medicines. Our Digital Product Development unit within Global Product Development is at the forefront of this transformation, utilizing digital tools to enhance productivity and sustainability. Join us and be part of a dynamic team that spans product development from late‑stage research to full‑scale manufacturing. Accountabilities In this pivotal role, you will collaborate with digital specialists, scientific experts, and project leaders across AstraZeneca’s global network. You will champion advanced modelling solutions and drive drug development from clinical trials to commercial production. Your key responsibilities will include: Translating complex pharmaceutical process problems into robust mechanistic models, providing actionable insights to accelerate drug development projects. Collaborating with experimental scientists from diverse backgrounds to uncover new modelling opportunities and strategically guide experimental design. Establishing strong, collaborative relationships within the digital and broader product development communities to maximize the transformative impact of modelling and simulation. Driving organizational digital transformation by advancing best practices and advocating for the application of cutting‑edge digital tools, including making them available to agentic AI systems. Developing, validating, and deploying modelling and simulation protocols to support scientists across the wider scientific community. Essential Skills/Experience MSc in chemical engineering, mechanical engineering, or related discipline, ideally with specialization in process modelling and several years of industry experience. PhD is preferred. Extensive knowledge of process modelling fundamentals and demonstrable experience applying these principles to the development of industrial‑scale products or processes. Proficiency in programming and simulation tools (such as Python, Matlab, gPROMS), with a readiness to explore emerging technologies. Strong collaboration, communication, influencing, and networking skills. Desirable Skills/Experience Industry experience within pharmaceuticals, biopharmaceuticals, food, cosmetics, personal care, or consumer goods. Experience with one or more of the following techniques: process modelling, discrete element modelling, computational fluid dynamics, system modelling, multiscale modelling, molecular dynamics. Comprehensive understanding of process equipment and technology. Demonstrated ability to proactively introduce and apply novel modelling approaches to advance product development and manufacturing. A track record of scientific publications in the field of modelling and simulation. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life‑changing medicines. In‑person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. SO, WHAT’S NEXT? Where can I find out more? Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/ Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/ Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en Are you ready to make a difference? Apply today and join us in our mission to improve global public health Date Posted: 02-Dec-2025 Closing Date: 08-Dec-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. #J-18808-Ljbffr