Associate Director, Evidence Synthesis

1 week ago


Manchester, United Kingdom Genesis Research Group Full time

Genesis is one of the leading evidence generation consultancies providing agile, tech-enabled real-world evidence (RWE), as well as health economics and outcomes research (HEOR) solutions to clients in the pharmaceutical, biotech, and medical device industries.
Since 2009, we've partnered with our clients to develop impactful evidence across the product lifecycle to optimize market access for novel healthcare innovations and satisfy regulatory, provider, and payer evidence requirements.
Genesis is database agnostic, regularly working across many structured and unstructured real-world data sources.
As a company, we deliver services across many RWE and HEOR applications and a wide range of therapeutic areas with an emphasis on uncompromising quality, scientific rigor, and flexible solutions.
The Genesis Evidence Synthesis (ES) team works exclusively on qualitative and, in collaboration with the Genesis Biostatistics and Analytics teams, quantitative evidence synthesis activities.
Our work includes systematic, structured, and targeted literature reviews, as well as meta-analysis, meta-regression, and indirect treatment comparisons (e.g.
network meta-analysis [NMA], matching adjusted indirect comparisons [MAIC], etc.).
The team works collaboratively with clients, their external stakeholders, and our broad team of internal experts to efficiently deliver rigorous research findings supporting varying needs in the pharmaceutical industry – competitive intelligence activities, database landscape assessments, disease and health economic modelling inputs, dossier development, internal strategy support, gap analysis, publications, HTA/payer/reimbursement submissions, regulatory submissions, and more.
The Genesis team has decades of combined experience, including a strong record of peer-reviewed publications and work in evidence synthesis.
Accountabilities within this role: Develops search strategies using online tools and databases (i.e.
Embase, Medline, Cochrane, preferably via Ovid); provides oversight for development and conduct of literature searches by junior team members.
Is knowledgeable of systematic and targeted literature review methodology and provides both guidance and oversight for identifying and selecting relevant published literature sources; oversees data extraction and either performs or oversees data validation/quality control steps.
Independently analyzes a large evidence base and draws considered conclusions, and mentors junior team members in critically evaluating the evidence base to identify key messages, as relevant to project objectives.
Independently leads preparation of high-quality written technical reports, in compliance with all company quality standards and processes, mentors junior team members in developing relevant sections or drafts.
Independently leads preparation of high-quality presentations, for use within the company and externally to client, and mentors junior team members in developing relevant sections or drafts.
Ensures all work is delivered with high-quality and within planned project timelines and/ or budgeted hours (if relevant).
Ensures proficient use of EndNote to manage referencing appropriately within reports.
Ensures proficient use of Microsoft Office applications to ensure clear and well formatted deliverables are delivered to clients.
Leads and/or attends relevant internal and/ or external team meetings.
Leads and/or contributes to the team's development of templates, new ideas and/ or process improvements related to literature review processes within the company.
Leads and/or contributes to the team's development of publications and/ or posters for national or international conferences.
Qualifications: 5+ years industry or consulting experience in evidence synthesis work, or, more broadly in market access/ HEOR, across multiple project types and disease areas.
Masters or PhD within a relevant discipline.
Excellent verbal and written communication skills, organizational skills and attention to detail.
Excellent time and project management skills, including setting of project goals, timelines, and budgeted hours.
Ability to work collaboratively across multiple, simultaneous projects and coordinate with various internal project teams, as well as stakeholder management skills, including ability to challenge diplomatically and appropriately.
Demonstrates problem-solving skills, showing an ability to find and employ effective, creative solutions and adjust course.
Embraces change as an opportunity for growth and innovation while maintaining a resilient and proactive attitude in a dynamic, changing, growth-oriented environment.
Demonstrates enthusiasm for learning and is motivated to take on opportunities to develop oneself, as well as others within the Genesis ES Team.
Demonstrates leadership in a matrix environment and flexibility to adapt to client project needs in a fast-paced entrepreneurial workplace.
Knowledge of or experience with quantitative evidence synthesis preferred (i e.g.
network meta-analysis [NMA], matching adjusted indirect comparisons [MAIC], etc.).
Technical knowledge of the market access/ HEOR environment, with specific UK/ European or US experience preferred, but not required.
Compensation: Competitive salary Performance-related bonus Flexible Paid Time Off Employer matched pension plan Private Medical Insurance Genesis Research is an equal opportunity employer.


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