RNA Synthesis Specialist

3 weeks ago


Cambridge, Cambridgeshire, United Kingdom ZipRecruiter Full time
RNA Synthesis and Analysis Researcher

We are seeking a highly motivated and experienced researcher to join our RNA Synthesis group and contribute to RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, as well as evaluate new chemical modifications for their use in the RNAi pathway.

Key Responsibilities:
  1. Design and Synthesis: Design and synthesize chemically modified oligonucleotides using various methods and techniques.
  2. Purification and Analysis: Utilize analytical instrumentation such as UV-Vis spectroscopy, HPLC, and LC-MS for the analysis of both crude and purified synthetic products.
  3. Method Development: Improve upon and/or develop new methods and automation for the downstream processing of synthetic oligonucleotides and their subsequent analysis/purification and annealing into siRNA duplexes.
  4. Data Analysis: Analyze, interpret, and organize analytical data to present to team members.
Qualifications:
  1. Education: Bachelor's or Master's degree in Chemistry, Biochemistry, or a related field.
  2. Experience: 0-4 years of work experience, preferably in an industrial setting.
  3. Skills: Strong commitment to high laboratory and scientific standards and the ability to maintain a safe, clean, and orderly laboratory work environment.

About Alnylam: Alnylam Pharmaceuticals is a leader in the development of RNAi therapeutics, with a focus on treating diseases at their genetic source. Our team is dedicated to advancing the field of RNAi research and developing innovative medicines that transform lives.



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