Molecular Biology Specialist
1 month ago
To provide expert technical support for the creation of inducible gene knockouts in human malaria parasites (Plasmodium falciparum) and advise on the setup and operation of equipment and procedures to achieve research objectives.
Main Duties and Responsibilities- Develop and implement streamlined molecular cloning protocols to produce transfection-ready plasmids at scale.
- Provide technical support for malaria culture work in a Containment Level 3 laboratory, including day-to-day maintenance of P. falciparum cultures and transfections.
- Maintain laboratory equipment, diagnose faults, and troubleshoot day-to-day problems relating to equipment, techniques, procedures, and protocols.
- Advise, implement, and evaluate improvements to existing protocols as required.
- Collect, analyze, and interpret data using standard procedures and ensure accurate research records are kept and databases are updated.
- Plan and organize day-to-day work to ensure experimental goals are delivered within agreed timescales.
- Supervise junior staff, instruct, train, and provide guidance to research staff and students in techniques and equipment operation.
- Contribute to the well-organized functioning of the laboratory and assist in maintaining stock levels and purchasing consumables and supplies within budget.
- Ensure the safe and efficient functioning of the laboratory area and facilities, including risk assessments and COSHH assessments.
- Collaborate with colleagues and participate in team meetings and departmental research group activities.
- Keep up to date with advancements in technology and methodology, updating technical knowledge.
Essential:
- Advanced Higher or HNC, SVQ 3, or equivalent in a relevant science subject.
- Detailed technical knowledge of molecular biology and cell/tissue culture techniques.
- Up-to-date knowledge of relevant laboratory Health and Safety legislation.
Desirable:
- BSc Degree or equivalent in a relevant scientific discipline.
- Knowledge of Equality and Diversity policy.
Essential:
- Skills in molecular biology.
- Skills in cell and tissue culture and aseptic techniques.
- IT, including familiarity with Microsoft Office programs and relevant databases.
- Demonstrable analytical and problem-solving abilities.
- Proven interpersonal and communication skills.
- Numeracy and literacy skills.
- A high level of accuracy and attention to detail.
- Excellent organizational and time management skills and ability to prioritize workload.
- Ability to work individually and as part of a team.
Desirable:
- Skills in high-throughput molecular cloning.
Essential:
- Significant relevant work experience in a research laboratory.
- Laboratory experience in core molecular biology techniques, including DNA/RNA extraction, PCR, gel electrophoresis, bacterial culture, and plasmid design and assembly.
- Experience of understanding and interpreting the technical requirements of staff and students.
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