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Principal PBPK Consultant

2 months ago

Sheffield, Sheffield, United Kingdom Certara Full time
About Certara

Certara is a leading provider of biosimulation software, technology, and services that accelerate medicines through the drug discovery and development process.

Our clients include over 2,000 biopharmaceutical companies, academic institutions, and regulatory agencies across 62 countries.

Job Description

We are seeking a highly motivated and talented PBPK modelling scientist or expert with a DMPK, PBPK, and/or biopharmaceutics modelling background to join our team.

The successful candidate will contribute to consultancy projects with clients in the Pharmaceutical Industry to develop PBPK models for particular projects of interest.

Responsibilities
  • Develop PBPK models for consultancy projects with clients in the Pharmaceutical Industry.
  • Apply PBPK models in support of various applications, including DDI liability prediction, food effect prediction, PK prediction in special populations, biopharmaceutics/bioequivalence prediction, and large molecule PK prediction.
  • Contribute to consultancy projects with supervision.
  • Stay up-to-date with the latest scientific developments in the area of PBPK and IVIVE to enable effective communication with colleagues, clients, and the wider scientific community.
Qualifications
  • PhD degree in a relevant field or equivalent experience in the field of IVIVE/drug metabolism/pharmacokinetics.
  • Knowledge of the application of PBPK modelling in the drug discovery and development process.
  • Understanding of IVIVE/drug metabolism/pharmacokinetics.
  • Sound overview of the simulator with good knowledge and understanding of specific areas.
  • Excellent communication skills to effectively engage with peers and clients within industry, academia, and regulatory agencies.
About Certara

Certara is an equal opportunities employer and welcomes applications from all qualified candidates. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.