Principal PBPK Consultant

1 week ago


Sheffield, Sheffield, United Kingdom Certara Full time
About the Role

The Certara Predictive Technologies PBPK consultancy team is a global organization focused on using the Simcyp physiologically-based pharmacokinetic (PBPK) platform to influence decision-making on drug development programs from discovery to regulatory filing. Our team works with hundreds of clients to inform human PK prediction, drug-drug interaction assessment, special population predictions, and biopharmaceutics strategy.

Responsibilities

The role involves contributing to consultancy projects with clients in the Pharmaceutical Industry to develop PBPK models for particular projects of interest. These models will be applied to support a number of applications, including but not limited to:
  • DDI liability prediction;
  • Food effect prediction
  • PK prediction in special populations
  • Biopharmaceutics/bioequivalence prediction
  • Large molecule PK prediction.

Qualifications

A PhD degree in a relevant field or equivalent experience in the field of IVIVE/drug metabolism/pharmacokinetics is required. The successful candidate should have some knowledge of the application of PBPK modeling in the drug discovery and development process, as well as excellent communication skills to effectively engage with peers and clients within industry, academia, and regulatory agencies. We treat all applicants and employees without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or other characteristic protected by law.

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